耐多药肺结核初始6个月疗效影响因素分析  

MULTIDRUG-RESISTANT PULMONARY TUBERCULOSIS:FACTORS INFLUENCING THE EFFICACY OF INITIAL SIX MONTHS OF THERAPY

作　　者：刘佩英[1] 王秀勤[1] 赵善良[1] 

机构地区：[1]临沂市人民医院结核内科,山东临沂276034

出　　处：《齐鲁医学杂志》2015年第3期343-344,共2页Medical Journal of Qilu

摘　　要：目的分析耐多药肺结核病人初始6个月疗效影响因素，以提高耐多药肺结核抗结核治疗的效果。方法评价61例耐多药肺结核病人初始6个月的疗效，找出影响疗效的因素。结果61例病人治疗6个月好转30例，好转率49．2％。影响耐多药肺结核病人疗效的危险因素有抗结核治疗史、空洞形成、消瘦、低血红蛋白血症、低清蛋白血症（χ2=4．075～7．634，t=-4．361，P〈o．05）。结论耐多药肺结核病人在抗结核治疗的同时应加强营养支持治疗，对药物不良反应及时采取措施加以处理，以提高病人治疗的依从性。Objective To analyze the factors influencing therapeutic effect of multidrug-resistant pulmonary tuberculosis （MDRPT） in initial 6 months of treatment, so as increase its efficacy. Methods An analysis was done in 61 patients with MDRPT concerning their efficacy and its influencing factors in initial 6 months of treatment. Results In the 61 patients treated for 6 months, 30 （49.2%） patients improved. Risk factors influencing the treatment outcomes were： history of anti-TB treatment, cavitation formation, became thin, hypohemoglobinemia, and hypoalhuminemia （χ2 = 4. 075 --7. 634, t = - 4. 361, P〈 0.05 ）. Conclusion For patients with pulmonary tuberculosis resistant to multidrugs, nutrition support should be strengthened while in the treatment of the illness, timely measures he taken to deal with the adverse reactions of the drugs in order to improve the com- pliance of patient treatment.

关 键 词：结核 抗多种药物性 治疗结果 因素分析 统计学 

分 类 号：R521[医药卫生—内科学]