系统性红斑狼疮病人焦虑抑郁与疾病状态相关性研究  

ANXIETY AND DEPRESSION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS:A CORRELATION STUDY

作　　者：刘勇华[1] 曾玲玲[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院皮肤科,湖北武汉430022

出　　处：《齐鲁医学杂志》2015年第3期351-352,355,共3页Medical Journal of Qilu

摘　　要：目的探讨系统性红斑狼疮(SLE)病人焦虑抑郁与疾病状态的关系。方法应用Zung氏焦虑自评量表(SAS)和抑郁自评量表(SDS)对在我科住院的108例SLE病人的心理状态进行评估,采用SLE疾病活动性指数(SLEDAI)对疾病活动度进行评估,并采用SPSS 18.0软件对数据进行统计分析。结果 SLE病人的SAS、SDS评分显著高于国内常模(t=8.46、4.24,P<0.01),并且与疾病活动度相关(r=0.201、0.242,P<0.05)。结论 SLE病人的心理健康水平较低,焦虑和抑郁明显,需进行积极有效的心理干预,以提高病人心理健康水平,降低疾病活动程度,从而提高生活质量。Objective To study the correlation between anxiety-depression and morbid state in patients with systemic lupus erythematosus （SLE）. Methods Using the self-rating Anxiety Scale （SAS） and the self-rating Depression Scale （SDS） to assess the mentation in 108 patients with SLE hospitalized in our hospital, and SLEDAI to assess the disease activity. The data obtained were analyzed by software SPSS version 18.0. Results The scores of SAS and SDS in the SLE patients were higher than the national norms （t=8.46,4.24;P〈0.01）, which were correlated with the activity of the disease （r=0.201,0.242;P〈0.05）. Conclusion The level of mental health in SLE patients is relatively low with obvious anxiety and depression. Taking an active and effective psychological intervention is needed to improve the patient mental health level and reduce the degree of disease activity, so as to improve the quality of life of the patients.

关 键 词：红斑狼疮 系统性 焦虑 抑郁 疾病活动度 心理疗法 

分 类 号：R593.24[医药卫生—内科学] R749[医药卫生—临床医学]