支气管动脉造影和栓塞术后造影剂肾病的危险因素分析  

Incidence and risk factors of contrast-induced nephropathy after bronchial arteriography or bronchial artery embolization

作　　者：何阳 曹军 赵保成 刘洪强 郑晓辉 王赛博 罗剑均[2] 颜志平[2] 

机构地区：[1]上海市大华医院介入肿瘤科,上海200237 [2]复旦大学附属中山医院介入科,上海200032

出　　处：《海南医学》2015年第11期1589-1591,共3页Hainan Medical Journal

基　　金：上海市卫生局青年科研项目(编号:20124Y096);上海市自然科学基金(编号:12ZR1428900)

摘　　要：目的了解支气管动脉造影和栓塞后造影剂肾病的危险因素。方法回顾性分析2012年1月至2013年12月间于徐汇区大华医院介入肿瘤科行支气管动脉造影或支气管动脉栓塞术的100例患者资料。将发生造影剂肾病和无造影剂肾病患者进行比较,对造影剂肾病的影响因素行单因素分析和多因素Logistic回归分析。结果 100例患者中88例符合入选标准,其中7例发生造影剂肾病(7.95%)。造影剂肾病发生的平均时间为(2.36±0.72)d。单因素分析显示,低白蛋白血症(P=0.002)、低血压(P=0.036)和肾功能衰竭(P=0.001)与造影剂肾病的发生显著相关,而多因素分析仅提示低白蛋白血症与造影剂肾病的发生显著相关(P=0.022 0)。结论造影剂肾病发生率高于预期,低白蛋白血症患者更需防范支气管动脉造影和栓塞后造影剂肾病的发生。Objective To analyze the risk factors of contrast-induced nephropathy （CIN） after bronchial ar-teriography or bronchial artery embolization. Methods We reviewed the medical records of 100 patients who un-derwent bronchial arteriography or bronchial artery embolization （BAE） in Shanghai Dahua Hospital from January 2012 to December 2013 retrospectively. The patients who suffered CIN and Those without CIN were then com-pared, and the risk factors of CIN were analyzed by single factor analysis and multivariate logistic regression analy-sis. Results Among the 100 patiens, 88 met the enrollment criteria, of which 7 patients developed CIN （8.0%）. The mean duration between the exposure and development of CIN was （2.36 ± 0.72） days. Hypoalbuminemia （P=0.002）, hypotension （P=0.036） and renal failure （P=0.001） were found to be significantly associated with the de-velopment of CIN according to single factor analysis, while hypoalbuminemia （P=0.0220） was the only factor found to be significantly associated with the development of CIN according to multivariate logistic regression analysis. Conclusion The incidence of CIN is higher than expected, and patients with hypoalbuminemia should be cared more carefully to prevent CIN after bronchial arteriography or BAE.

关 键 词：造影剂肾病 急性肾损伤 支气管动脉造影 支气管动脉栓塞 低白蛋白血症 

分 类 号：R692[医药卫生—泌尿科学]