神经节苷脂钠治疗新生儿颅内出血34例疗效观察  

Clinical effects of ganglioside in the treatment of neonatal intracranial hemorrhage

作　　者：朱樱梅[1] 谢伊玲[1] 张兰[1] 

机构地区：[1]东莞市妇幼保健院儿科,广东东莞523000

出　　处：《海南医学》2015年第11期1684-1685,共2页Hainan Medical Journal

摘　　要：目的探讨神经节苷脂钠治疗新生儿颅内出血的临床疗效。方法 68例颅内出血患儿随机分为观察组和对照组各34例,对照组给予常规治疗,观察组在对照组基础上加用单唾液酸四己糖神经节苷脂钠治疗,14 d后比较两组患儿的临床疗效及新生儿神经行为测定评分(NBNA评分)。结果观察组治疗总有效率为94.12%,明显高于对照组的73.53%,差异有统计学意义(P<0.05)。观察组患儿的NBNA评分正常率为91.18%,明显高于对照组的70.59%,差异有统计学意义(P<0.05)。结论神经节苷脂钠治疗新生儿颅内出血能够有效改善患儿神经行为,促进患儿神经发育,疗效肯定,值得推广。Objective To discuss the clinical effects of ganglioside in newborns with intracranial hemor-rhage. Methods Sixty-eight newborns with intracranial hemorrhage were randomly divided into the observation group （n=34） and the control group （n=34）. The control group was treated with conventional treatment, while the ob-servation group was treated with ganglioside based on conventional treatment. Clinical effects and NBNA score were contrasted between the two groups 14 days after the treatment. Results The total effective rate in the observation group was 94.11%, which was significantly higher than 73.52% in the control group （P〈0.05）;The normal rate of NBNA score in the observation group was 91.18%, significantly higher than 70.59%in the control group （P〈0.05）. Conclusion Ganglioside can effectively improve nerve behavior and promote neurodevelopment in the treatment of neonatal intracranial hemorrhage. Therefore it was curative and worthy of promotion.

关 键 词：神经节苷脂钠 新生儿 颅内出血 

分 类 号：R722.12[医药卫生—儿科]