高浓度补钾对危重低钾血症患者疗效及预后情况的影响分析  

The effects of high concentration potassium supplementation on curative outcomes and prognosis in critically ill patients with hypokalemia

作　　者：邹宇君[1] 

机构地区：[1]广东省农垦中心医院ICU,广东湛江524002

出　　处：《右江民族医学院学报》2015年第3期404-405,410,共3页Journal of Youjiang Medical University for Nationalities

摘　　要：目的：研究不同补钾方案对危重低钾血症患者的临床疗效及预后情况的影响。方法选择2010年2月~2013年2月在我院接受治疗的危重低钾血症患者112例作为研究对象。根据数字法随机分成观察组及对照组各56例,为两组患者均开通其静脉通道,对照组患者使用 KCl 注射液输注补钾,观察组使用门冬氨酸钾注射液输注补钾。对比两组补钾24 h 后相关指标,两组不同时间血钾水平上升比例,两组主要并发症发生情况以及预后情况。结果两组治疗前的血钾水平相比,差异无统计学意义（P〉0.05）。治疗后观察组的血钾水平显著高于对照组,24 h 输液量显著少于对照组,差异均有统计学意义（P 均〈0.001）。观察组12 h 血钾升至3 mmol/L 的比例为71.43%,显著高于对照组的23.21%,差异有统计学意义（P 〈0.001）。观察组总并发症的发生率为1.79%,显著低于对照组的12.50%,差异有统计学意义（P 〈0.05）。结论门冬氨酸钾补钾方案可使危重低钾血症患者获得更佳疗效,且可有效减少不良并发症预后情况,效果明显,值得推广。Objective To study the impact of different potassium supplementation on curative outcomes and prognosis in critically ill patients with hypokalemia. Methods February 2012 to February 2013 a total of 1 12 critically ill patients with hypokalemia cared at our hospital were selected as the research objects.The pa-tients were randomly divided into an observation group and a control group with 56 cases in each group by using a number method,patients of the two groups were opened the venous channels,patients in the control group received KCL Injection infusion for potassium supplementation,the observation group used Potassium Aspar-tate Injection infusion for potassium supplementation.Compared of the related indexes at different time 24 h af-ter potassium supplement between the two groups,and compared of serum potassium increased proportion at different time points between the two groups,the main complications and the prognosis between the two groups. Results Compared of pre-treatment serum potassium level between the two groups,there was no statistically significant difference（P 〉0.05）.Blood potassium levels in the observation group after treatment was significantly higher than the control group,24-hour infusion volume was significantly less than the control group,group-paired comparison yielded statistically significant difference（all P 〈0.001）.71.43% of the ob-servation group patients had 12 -hour potassium rising to 3mmol/L,which was significantly higher than the control group of 23.21%,the difference was statistically significant（P 〈0.001）.The observation group＆#39;s total complication rate was 1.79%,which was significantly lower than 12.50% of the control group,the difference was statistically significant（P 〈0.05）. Conclusion Potassium Aspartate potassium can get better results for severe hypokalemia patients,and can effectively reduce the adverse complications and improve prognosis,and it is worthy of clinical recommendation.

关 键 词：门冬氨酸钾 危重症 低钾血症 

分 类 号：R591.1[医药卫生—内科学]