颈椎四节段混合术的力学特性及耦合规律  

Biomechanical characteristics of four-level cervical hybrid construct versus fusion:An in vitroinvestigation

作　　者：廖振华[1,2] 蒲婷 玮娜[2,4] 颜滨[5] 刘伟强[1,2] 

机构地区：[1]清华大学机械工程系,北京100084 [2]深圳清华大学研究院深圳清华大学研究院,深圳518057 [3]机科发展科技股份有限公司,北京100044 [4]清华大学深圳研究生院,深圳518055 [5]深圳市第二人民医院,深圳518049

出　　处：《清华大学学报（自然科学版）》2015年第2期231-236,共6页Journal of Tsinghua University(Science and Technology)

基　　金：“十二五”国家科技支撑计划资助项目(2012BAI18B05)

摘　　要：为研究人体颈椎四节段混合术后手术节段与相邻节段的运动特性及耦合规律,采用12具人体颈椎标本,通过三维非接触式光电测量系统及位移控制方式,测试初始态(intact)、四节段混合术(C3-C4置换,C4-C6融合,C6-C7置换)及四节段融合术(C3-C7融合)术后各节段在6种独立工况的运动分布,并对颈椎生理运动规律及耦合特性进行探讨。结果表明:与四节段融合术相比,四节段混合术能显著避免相邻节段运动激增,手术节段运动得到一定程度保留,整体具有更接近初始状态的运动分布和耦合特性,生物力学性能更优。This study analyzed the cervical spine kinematics after 4-level hybrid constructs compared the results with the kinematics after 4-level anterior cervical discectomy and fusion. Twelve human cadaveric spines were evaluated using three-dimensional optoelectronics measurements for an intact spine, a 4-level hybrid construct （C3-C4 disc replacement, C4 C6 plate, C6-C7 disc replacement） and a 4-level fusion （C3-C7 plate）. The motion characteristics of the normal cervical spine and the coupled motion are also discussed. Although the 4-Ievel hybrid construct restored only part of the native kinematics of the cervical spine, this construct generated better biomechanical conditions than the 4-level fusion at adjacent levels by limiting contributions of these segments to the global range of motion.

关 键 词：颈椎 四节段 混合术 生物力学 耦合运动 

分 类 号：R318.19[医药卫生—生物医学工程]