血糖变异性与重症脑出血患者预后的临床研究  

Clinical study between blood glucose fluctuation and prognosis of severe cerebral hemorrhage patients

作　　者：赵慧新[1] 邸卫英[1] 袁蓓[1] 崔蕾[1] 张杏红[1] 闫奕[1] 宋月平[1] 

机构地区：[1]河北大学附属医院,河北保定071000

出　　处：《医学研究与教育》2015年第3期22-25,共4页Medical Research and Education

基　　金：河北省医学适用技术跟踪项目(GL102312)

摘　　要：目的探讨血糖变异性与重症脑出血患者预后的关系。方法对河北大学附属医院神经内科58例重症脑出血患者有无机械通气、住院时间、急性生理与慢性健康评估Ⅱ(APACHE Ⅱ)等临床资料进行分析。按预后分为存活组(n=41)和死亡组(n=17)两组。记录所有患者的初始血糖值、血糖值、血糖标准差、变异系数,用血糖标准差及变异系数来衡量血糖变异性。探讨血糖变异性与死亡的关系。结果死亡组与存活组比较,有无机械通气、住院时间、APACHEⅡ评分差异有统计学意义(P<0.05)。死亡组血糖标准差、变异系数均高于存活组(P<0.05)。结论血糖变异性与重症脑出血患者的预后密切相关。Objective To discuss the correlation between blood glucose fluctuation and prognosis of severe cerebral hemorrhage patients. Methods 58 patients with severe cerebral hemorrhage were selected as subjects. The clinical characteristics of all the patients were analyzed, such as mechanical ventilation, days of hospitalization, acute physiology and chronic health evaluation II （APACHE II） score. Those patients were divided into two groups： survival group （n=41） and death group （n=17）. Initial blood glucose, blood glucose value, mean number of blood glucose, standard deviation of blood glucose and variation coefficient of blood glucose were recorded. Standard deviation and variation coefficient of blood glucose were used as glucose variability index to explore the correlation between blood glucose fluctuation and death. Results Mechanical ventilation, days of hospitalization, APACHE II score in death group were higher than the control group （ P〈0.05 ）. Standard deviation and variation coefficient of blood glucose in death group were significantly higher than that of the survival group （P〈0.05 ）. Conclusion Blood glucose fluctuation and severe cerebral hemorrhage in the patients may be closely correlated with prognosis.

关 键 词：血糖变异性 脑出血 死亡 

分 类 号：R5[医药卫生—内科学]