Genistein对结肠癌细胞抑制作用及其机制研究进展  

Advances on inhibitory effects of Genistein on colon cancer cell and its mechanism

作　　者：李维维[1] 史睿亭 吴素焕[2] 

机构地区：[1]河北大学临床医学院,河北保定071000 [2]河北大学基础医学院,河北保定071000

出　　处：《医学研究与教育》2015年第3期87-90,104,共5页Medical Research and Education

基　　金：河北大学大学生创新创业训练项目(2013089)

摘　　要：三羟异黄酮(Genistein)是一种存在于豆科植物和齿状植物中的雌激素类天然异黄酮化合物。具有广泛的抗肿瘤药理活性,对肿瘤的预防和治疗有很重要的意义。参阅大量近年来国内外相关文献,就Genistein对结肠癌细胞的抑制作用及作用机制的最新研究进展予以综述。Genistein is a kind of estrogen natural isoflavone compounds which exists in the leguminous and dentate plants. It is significant to the prevention and treatment of cancer with wide anticancer pharmacological activities. In this paper, we summarize the latest research progress of the effects of Genistein on cell inhibitory and its mechanism of colon cancer cell on the basis of a large number of recent references at home and abroad.

关 键 词：三羟异黄酮 抗肿瘤 结肠癌 抑制 作用机制 

分 类 号：R91[医药卫生—药学]