脑尔新胶嚢治疗精神分裂症的初步临床观察  

Clinical Effect of Naoerxin Capsule on the Treatment of Schizophrenia

作　　者：李新纯[1] 王超英[1] 李庆 刘学军[1] 郭田生[1] 唐武 涂远生 

机构地区：[1]湖南省脑科医院湖南中医药大学附属临床医学院,湖南省中西医结合精神病学实验室,湖南长沙410007 [2]湖南省中医院,湖南长沙410005 [3]湘潭市中心医院,湖南湘潭411100 [4]洪江中医药研究所,湖南怀化418200

出　　处：《湖南中医药大学学报》2015年第3期57-59,共3页Journal of Hunan University of Chinese Medicine

基　　金：湖南省中医药管理局基金项目(201173)

摘　　要：目的探讨脑尔新胶囊治疗精神分裂症的临床疗效。方法将中医辨证为狂病,痰火扰神证的偏执型、未分化型精神分裂症患者64例随机分为脑尔新胶囊观察组和利培酮对照组各32例,疗程6周。观察比较两组治疗前后阴性症状和阳性症状量表(PANSS)评分的变化、临床疗效及副反应量表(TESS)评分。结果治疗后两组PANSS评分均较治疗前显著下降(P<0.01),组间比较差异无统计学意义(P>0.05);观察组总有效率为80.0%,对照组为83.3%,两组差异无统计学意义(P>0.05);观察组TESS评分明显低于对照组(P<0.05)。结论脑尔新胶囊治疗首发偏执型精神分裂症疗效确切,副反应发生率低,耐受性较好。Objective To assess the efficacy of Naoerxin capsule in the treatment of schizophrenia. Methods 64 patients with madness, Tanhuo Shaoshen type paranoid and undifferentiated schizophrenia were randomly assigned to the observation group（Naoerxin capsule） and control group（risperidone）, 32 patients in each group, and the curse was for 6weeks. The changes in PANSS score, clinical effect, TESS score were observed before and after the treatment. Results The PANSS score were reduced significantly after treatment（P〈0.01）. The treatment effect had no significant differences between two groups（P〉.05）. The total effective rate was 80.00% in the observation group, and 83.33% in the control group. There was no significant difference between the two groups（P〉0.05）. The TESS score in the observation group was lower obviously than the control group（P〉0.05）. Conclusion Naoerxin capsule showed good effect in treatment of newly diagnosed paranoid schizophrenia. The drug displayed low adverse effect rate and was well tolerated.

关 键 词：精神分裂症 脑尔新胶囊 利培酮 狂病 痰火扰神证 

分 类 号：R277.7[医药卫生—中医学] R749.3