于术化学成分研究  

Chemical Constituents of Atractylodes Macrocephala from Yuqian

作　　者：王亚男[1] 张娜[1] 窦德强[1] 

机构地区：[1]辽宁中医药大学,辽宁大连116600

出　　处：《辽宁中医药大学学报》2015年第7期52-54,共3页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家重点基础研究发展计划(973计划)项目(2013CB531803);辽宁省高等学校创新团队课题(LT2013020)

摘　　要：目的:对浙江于潜产白术的化学成分进行研究。方法:采用乙醇回流法提取,经硅胶柱色谱及制备高效液相色谱法等进行分离纯化,并通过理化常数测定和波谱分析鉴定其化学结构。结果:从浙江于潜产白术中分离鉴定了7个化合物,分别为:(1)蒲公英萜醇乙酸酯、(2)白术内酯Ⅱ、(3)邻苯二甲酸二异丁酯、(4)邻苯二甲酸二丁酯、(5)杜松脑、(6)白术内酯Ⅰ、(7)白术内酯Ⅲ。结论:化合物(3)、(4)为首次从苍术属植物白术中分离得到。Objective：To investigate the chemical constituents of Atractylodes macrocephala from Yuqian,Zhejiang. Methods：The dried rhizome of Atractylodes macrocephala was extracted with the method of ethanol refluxing. The constituents were isolated and purified by column chromatography on silica gel,RP-HPLC. The structures were identified by physicochemical properties and spectrum analysis. Results：Seven compounds were isolated and their structures were identified as（1）taraxasteryl acetate,（2）atractylenolide Ⅱ,（3）diisobutyl phthalate,（4）dibutyl phthalate,（5）juniper camphor,（6）atractylenolideⅠ,（7）atractylenolideⅢ. Conclusion：Compound 3,4 were isolated for the first time from Atractylodes macrocephala.

关 键 词：白术 化学成分 结构鉴定 白术内酯 

分 类 号：R284[医药卫生—中药学]