不同碘对比剂在子宫输卵管造影术中的对比研究  

Contrasted research of iodized oil and nonionic iodinated contrast media in hysterosalpingography

作　　者：张昌余[1] 白万晶[2] 宁刚[2] 李开明[2] 赵福敏[2] 李学胜[2] 

机构地区：[1]四川省德阳市人民医院门诊普外科,618000 [2]四川大学华西第二医院放射科,成都610041

出　　处：《中华妇幼临床医学杂志（电子版）》2015年第3期98-101,共4页Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)

摘　　要：目的探讨不同种类碘对比剂对子宫输卵管造影术(HSG)图像质量与不良反应的影响。方法随机选取2003年5月至2011年11月因不孕至四川大学华西第二医院就诊的99例患者为研究对象,按照其于HSG中使用的不同碘对比剂,将其分为A组(n=33,采用碘化油注射液)、B组(n=33,采用碘帕醇注射液)和C组(n=33,采用碘海醇注射液)。本研究遵循的程序符合四川大学华西第二医院人体试验委员会所制定的伦理学标准,得到该委员会批准,分组征得受试对象本人的知情同意,并与之签署临床研究知情同意书。记录3组患者HSG图像质量评分及不良反应。结果 199例患者中,宫腔黏连患者为22例(22.2%),输卵管病变为53例(53.5%)。2A组HSG图像质量评分为(2.5±0.5)分,B组为(2.4±0.5)分,C组为(2.2±0.4)分,3组比较,差异有统计学意义(H=6.680,P=0.034)。33组患者不良反应比较,差异有统计学意义(χ2=7.155,P=0.028)。结论 3种碘对比剂均可应用于HSG检查。对于非离子型碘对比剂,碘浓度越高,图像对比度越好,图像质量更佳。采用40%碘化油注射液所得HSG图像质量最好,但不良反应明显。Objective To discuss the image quality and adverse effects among different kinds of iodinated contrast media in hysterosalpingography（HSG）.Methods From May 2003 to November 2011,a total of 99 female infertile patients were included in the study.They were divided into three groups according to different iodinated contrast media in HSG,group A（n=33,40%iodized oil）,group B（n=33,iopamidol injection）and group C（n=33,iohexol injection）.The HSG image quality and adverse effects were recorded.The study protocol was approved by the Ethical Review Board of Investigation in Human Being of West China Second University Hospital.Informed consent was obtained from each participants.Results ①HSG results of 22cases（22.2%）showed intrauterine adhesion,53cases（53.5%）showed infertility.②The scores of HSG image quality was（2.5±0.5）score in group A,（2.4±0.5）score in group B,（2.2±0.4）score in group C,and the differences were significant among three groups（H=6.680,P=0.034）.③There were significant differences among three goups in adverse effects（χ^2=7.155,P=0.028）.Conclusions Three kinds of iodinated contrast media can all be applied in HSG.For nonionic iodinated contrast media,the higher of iodinated concentration,the better of image contrast,which makes image quality much better.For 40%iodized oil,the image quality was the best but the adverse effects were obvious.

关 键 词：子宫输卵管造影术 对比剂 图像质量 不良反应 

分 类 号：R816.91[医药卫生—放射医学] R711.6[医药卫生—临床医学]