连续性血液净化对多发性创伤并发MODS的疗效分析  

The Effect Analysis of Continuous Blood Purification on Multiple Trauma Complicated with MODS

作　　者：郭锻强[1] 张远新[1] 黄敏坚[1] 

机构地区：[1]广州医科大学附属第一医院,广东广州510120

出　　处：《中外医学研究》2015年第18期38-39,共2页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨连续性血液净化治疗(continuous blood purification,CBP)在多发性创伤并发多器官功能障碍综合征(multiple organ dysfunction syndrome,MODS)患者中的应用价值。方法:分析笔者所在医院急诊科收治的多发性创伤合并MODS患者32例,进行连续性血液净化治疗,观察治疗前及治疗后12、24 h平均动脉压(MAP)、生化指标、血气分析及血清TNF-α水平,进行对照分析。结果:MODS患者行CBP治疗24 h后临床症状得到明显改善或缓解;MAP升高,肌酐(Cr)、BUN、K+、血气分析及血清TNF-α水平明显降低,与治疗前差异均有统计学意义(P<0.05)。结论:积极对创伤常规治疗的同时早期采用CBP可显著改善MODS患者的病情,纠正受损脏器的功能障碍,减少并发症,提高抢救成功率。Objective：To investigate the application value of continuous blood purification（CBP） in multiple trauma complicated with multiple organ dysfunction syndrome（MODS）.Method：32 cases of multiple trauma complicated with MODS admitted to the emergency department of our hospital were analyzed,they treated with continuous blood purification treatment,before treatment and after treatment 12,24 hours mean arterial pressure（MAP）,biochemical index,blood gas analysis and serum TNF-levels were observed and analyzed.Result：After 24 h of CBP treatment,the clinical symptoms were improved or alleviated;the MAP was increased,the serum creatinine（Cr）,BUN,K＋,blood gas analysis and serum TNF-levels were reduced,compared with prior treatment,the differences were statistically significant（P〈0.05）.Conclusion：Positive to trauma and normal treatment early use of CBP can significantly improve symptoms of multiple trauma with MODS,can correct impaired organ dysfunction,reduce the complications,improve the success rate of rescue.

关 键 词：多发性创伤 多脏器功能失常综合征 连续性血液净化治疗 

分 类 号：R641[医药卫生—外科学]