韶关市哨点医院病毒性腹泻病原学特征分析  

Etiological characteristics of viral diarrhea in Shaoguan city

作　　者：邱灿林[1] 曾鑫[1] 徐子强[1] 徐亮[1] 

机构地区：[1]韶关市疾病预防控制中心,广东韶关512028

出　　处：《热带医学杂志》2015年第5期708-710,共3页Journal of Tropical Medicine

摘　　要：目的了解本地区病毒性腹泻的病原体分布情况,为制订防控对策提供依据。方法 2012年1月至2013年12月从韶关市粤北人民医院收集感染性腹泻患者的粪便标本,采用ELISA方法检测轮状病毒（RV）,采用荧光定量RT-PCR方法检测诺如病毒（NV）。结果共检测粪便标本431例,阳性数为242例,总阳性率为56.15%,其中轮状病毒和诺如病毒阳性率分别为29.7%、36.19%,两种病毒阳性率差异有统计学意义（χ2=4.12,P〈0.05）;轮状病毒流行主要在秋冬季,诺如病毒则主要在夏秋季;0~岁组阳性率最高,各年龄组间阳性率差异无统计学意义（χ2=0.01~1.39,P〉0.05）。结论病毒性腹泻病原体以诺如病毒和轮状病毒为主,诺如病毒感染以GⅡ型为主,;婴幼儿和老年人应该加强病毒性腹泻的监测。Objective To understand the distribution of the main pathogens of viral diarrhea,and provide basis for taking preventive measures.Methods The feces samples were collected from infected patients in Yue Bei people’s Hospital.Rotavirus was detected by ELISA; norovirus was detected by Real-time PCR. Results 431 samples were analyzed, with242 positive for viral detection. The positive rates of rotavirus, norovirus were 29.7% and 6.19%, respectively, showing significant difference（χ2=4.12, P〈0.05）. The prevalence of rotavirus was mainly in the fall and winter; norovirus was in the summer and fall. The highest positive rate of viral infection was in the age group of zero. There were no significant differences among the age groups（χ2=0.01~1.39, P〉0.05）. Conclusion Norovirus and rotavirus were the main pathogen causing viral diarrhea. The main type of norovirus was G Ⅱ. Monitoring of viral diarrhea in infants and the elderly should be strengthened.

关 键 词：轮状病毒 诺如病毒 病毒性腹泻 病原学 

分 类 号：R512.5[医药卫生—内科学]