2013-2014年梅州市诺如病毒感染性腹泻监测分析  

Surveillance of norovirus infectious diarrhea in Meizhou city,2013-2014

作　　者：杨翼龙[1] 廖伟东[1] 

机构地区：[1]梅州市疾病预防控制中心,广东梅州514071

出　　处：《热带医学杂志》2015年第5期711-713,共3页Journal of Tropical Medicine

摘　　要：目的了解梅州市诺如病毒感染性腹泻流行病学特征。方法收集2013年4月至2014年12月期间梅州市感染性腹泻哨点医院监测门诊的腹泻病例的粪便标本,采用实时荧光定量RT-PCR检测诺如病毒GⅠ和GⅡ基因组。结果共收集腹泻病例粪便标本766份,诺如病毒核酸检测阳性92份,阳性率为12.01%;阳性标本中诺如病毒基因型GⅡ型91份(98.91%),GⅠ型1份(1.09%)。全年均可检出诺如病毒,病毒检测阳性率高峰期集中在9-11月。不同性别间、不同年龄组之间诺如病毒检出阳性率差异无统计学意义(χ2=1.51,P>0.05,χ2=2.30,P>0.05)。结论诺如病毒是梅州市感染性腹泻常见病原,GⅡ型基因型为优势流行株;诺如病毒感染性腹泻全年均可发生,高峰期出现在秋冬季节;人群对诺如病毒普遍易感。Objective To monitor the epidemiological characteristic of norovirus infection diarrhea in Meizhou city.Methods The stool samples were collected from outpatients of acute diarrhea in sentinel hospital between 2013 and 2014. One step real-time RT-PCR was used for screening norovirus genogroups GI and GII. Results A total of 766 fecal specimens were included in this study; out of which, 92（12.01%） were positive for norovirus. Of 92 noroviruspositive specimens, 91（98.91%） were positive for genogroup GII and 4（1.09%） were positive for genogroup GI.Norovirus was prevalent throughout the year and an increased activity of norovirus infection was usually observed between September and Novermber. No statistically significant difference were observed in positive incidence of genders（χ2=1.51,P 〉0.05） and different age groups（χ2=2.30,P 〉0.05）. Conclusion Norovirus is a common causative agent responsible for infectious diarrhea in Meizhou, and genogroup GII is the dominant strain. Norovirus infection diarrhea is epidemic year round with high activity in autumn and winter.People are generally susceptible to norovirus infection.

关 键 词：诺如病毒 感染性腹泻 流行病学特征 

分 类 号：R512.5[医药卫生—内科学]