机构地区:[1]南昌市第一医院超声科,330008 [2] 南昌大学第一附属医院超声诊断科
出 处:《中国医药》2015年第7期942-945,共4页China Medicine
摘 要:目的 探讨左心房容积指数(LAVI)预测不稳定型心绞痛患者发生主要不良心血管事件(MACE)的价值.方法 纳入南昌市第一医院2012年1月至2013年9月收治的不稳定型心绞痛患者178例,根据LAVI将患者分成A组(LAVI≥32 ml/m2,86例)和B组(LAVI< 32 ml/m2,92例).比较A组和B组患者一般资料及超声心动图指标差异,随访患者住院期间及出院后12个月内发生MACE情况,分析MACE的独立危险因素.结果 A组左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVEDS)、肺静脉口Ar峰、二尖瓣口E峰、四腔心和二腔心左心房面积大于B组,左心房前后径和上下径小于B组[(55±4) mm比(48 ±5) mm,(35±5)mm比(29 ±6)mm,(27±6)cm/s比(25±6) cm/s,(78±20) cm/s比(73±16) cm/s,(22.9±0.9)mm2比(22.0±1.3)mm2,(21.8±1.1) mm2比(20.7±1.4)mm2,(44±3)mm比(47±5)mm,(31±4)mm比(33 ±4)mm;均P<0.05];A组高血压和糖尿病患者比例、肌酸激酶和肌酸激酶同工酶水平、接受经皮冠状动脉介入术(PCI)治疗比例高于B组[64.0% (55/86)比58.7% (54/92),66.3% (57/86)比63.0% (58/92),(172±35) U/L比(83±33) U/L,(19±6)U/L比(13±4)U/L,69.8%(60/86)比66.3%(61/92)],体质量和白细胞计数低于B组[(50±8)kg比(60±10) kg,(9.3±3.2)×109/L比(10.3±3.3)×109/L](均P<0.05).随访过程中共发生MACE事件70例,其中A组53例,B组17例,发生MACE患者中LAVI、LVEDD、LVEDS、肌酸激酶、肌酸激酶同工酶、糖尿病患者比例均高于未发生MACE患者,接受PCI治疗比例低于未发生MACE患者,差异有统计学意义[(36.3±2.6)ml/m2比(28.7±3.3) ml/m2,(53.4±1.9)mm比(49.9±2.1)mm,(36.7±1.6)mm比(34.8±1.5)mm,(199±14) U/L比(70±11) U/L,(19±7)U/L/(9±3)U/L,80.0%(56/70)比38.9% (42/108),68.6% (48/70)比80.6%(87/108)](均P<0.05).预测不稳�Objective To investigate the value of left atrial volume index (LAVI) in predicting the major adverse cardiovascular events (MACE) in unstable angina patients.Methods Totally 178 patients with unstable angina from January 2012 to September 2013 were enrolled and divided into group A (LAVI ≥ 32 ml/m2,86 cases) and group B (LAVI 〈 32 ml/m2,92 cases).The clinical data and echocardiography indices were compared between the two groups.All patients were followed up for 12 months to observe the major adverse cardiovascular events (MACE) and the independent risk factors were analyzed.Results The left ventricular end diastolic diameter (LVEDD),left ventricular end-systolic diameter (LVEDS),pulmonary vein orifice Ar peak,mitral valve orifice E peak,left atrial area on four chamber and two chamber view were larger,the anteroposterior diameter and vertical diameter of left atrial diameters were shorter in group A compared with those in group B [(55 ±4) mm vs (48 ±5) mm,(35 ±5) mm vs (29 ±6) mm,(27 ±6)cm/s vs (25 ±6)cm/s,(78 ±20)cm/s vs (73 ± 16)cm/s,(22.9±0.9) mm2 vs (22.0±1.3) mm2,(21.8±1.1) mm2 vs (20.7±1.4) mm2,(44±3) mmvs (47± 5) mm,(31 ±4) mm vs (33 ±4) mm] (all P 〈0.05).The proportion of hypertension and diabetes,levels of creatine kinase (CK) and CK-MB,the proportion of patients receiving percutaneous coronary intervention (PCI) were higher[64.0% (55/86) vs 58.7% (54/92),66.3% (57/86) vs 63.0% (58/92),(172 ±35)U/L vs (83 ± 33)U/L,(19±6)U/L vs (13±4)U/L,69.8% (60/86) vs 66.3% (61/92)],the weight and white blood cell count were lower in group A compared with those in group B[(50 ±8)kg vs (60 10)kg,(9.3 ±3.2) × 109/L vs (10.3 ± 3.3) × 109/L] (all P 〈 0.05).During 12-month follow-up,MACE occurred in 70 cases,including 53 cases of group A and 17 cases of group B.The LAVI,LVEDD,LVEDS,CK,CK-MB,the proportion of diabetes were higher
关 键 词:不稳定型心绞痛 左心房容积指数 主要不良心血管事件
分 类 号:R541.4[医药卫生—心血管疾病]
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