国内腹腔镜袖状胃切除术治疗肥胖症近期疗效的Meta分析  

Short-Term Effect of Laparoscopic Sleeve Gastrectomy for Obesity in China: A Meta Analysis

作　　者：杨志伟[1] 孙兆丹[2] 朱大勇[1] 宋海彬[1] 陈杨[1] 毛晓光[1] 

机构地区：[1]黑龙江省医院香坊院区普外二科,黑龙江哈尔滨150036 [2]黑龙江省疾病预防控制中心免疫规划所,黑龙江哈尔滨150030

出　　处：《中国普外基础与临床杂志》2015年第6期676-682,共7页Chinese Journal of Bases and Clinics In General Surgery

基　　金：黑龙江省卫生计生委科研课题(项目编号:2014-136)~~

摘　　要：目的探讨国内腹腔镜袖状胃切除术治疗肥胖症的近期疗效。方法制定检索策略,对万方、知网、Pub Med及Web of Science数据库进行检索,按照纳入标准和排除标准筛选文献,提取纳入文献的相关数据,并对其进行方法学质量评价和Meta分析。结果共纳入12篇文献、383例患者。Meta分析结果显示,LSG术前的体质量指数(BMI)高于术后6个月的BMI(MD=7.56,95%CI:5.77~9.34,P<0.000 01),LSG术后6个月的BMI高于术后12个月的BMI(MD=3.19,95%CI:2.20~4.18,P<0.000 01);LSG术后1个月的多余体质量减少百分比(EWL%)低于术后6个月的EWL%(MD=-42.77,95%CI:-45.77^-39.77,P<0.000 01),LSG术后6个月的EWL%低于术后12个月的EWL%(MD=-19.71,95%CI:-25.54^-13.87,P<0.000 01)。随着随访时间的延长,BMI呈逐渐下降的趋势,但EWL%却呈逐渐上升的趋势。结论在国内,腹腔镜袖状胃切除术治疗肥胖症患者的近期减重效果较好。Objective To investigate the short-term effect of laparoscopic sleeve gastrectomy（LSG） in treatment of obesity in China. Methods Literatures about the effect of LSG in treatment of obesity were searched from Wan Fang, CNKI, Pub Med, and Web of Science, then these literatures were filtered according to the inclusive and exclusive criteria and evaluated. Meta analysis was performed based on data extracted from these literatures. Results Three hundreds and eighty three cases of LSG were retrieved from 12 literatures. Compared with the preoperative, the body mass index（BMI） was lower in 6 months after LSG（MD=7.56, 95% CI： 5.77-9.34, P〈0.000 01）, and compared with 6 months after LSG, the BMI was lower in 12 months after LSG（MD=3.19, 95% CI： 2.20-4.18, P〈0.000 01）. Compared with 1 months after LSG, the excess weight loss（EWL%） was higher in 6 months after LSG（MD=-42.77, 95% CI：-45.77--39.77, P〈0.000 01）, and compared with 6 months after LSG, EWL% was higher in 12 months after LSG（MD=-19.71, 95% CI：-25.54--13.87, P〈0.000 01）. After the LSG, BMI decreased, but EWL% increased over time. Conclusions In China, LSG has obviously short-term curative effect in the treatment of obesity.

关 键 词：腹腔镜袖状胃切除术 肥胖症 近期疗效 META分析 

分 类 号：R656.61[医药卫生—外科学]