3-甲基-2-丁烯-1-醇的制备新工艺  

A new process on the preparation of 3-methyl-2-butene-1-ol

作　　者：周宝强[1] 宋林林[1] 张楠[1] 高瑞昶[1] 

机构地区：[1]天津大学化工学院,天津300072

出　　处：《化工进展》2015年第1期229-233,共5页Chemical Industry and Engineering Progress

摘　　要：研究了以溴代异戊烯水解工艺和精馏分离工艺为基础来制备3-甲基-2-丁烯-1-醇的新工艺。通过优化溶剂种类得到当水解溶剂为偶极类溶剂乙腈时,得到产物的选择性最高。并通过进一步优化实验操作条件,得到当溶剂加入量为v(乙腈):v(溴代异戊烯)=1∶1,水解温度为70℃,碱用量为n(Na OH)∶n(溴代异戊烯)=1.2∶1和反应时间为25min时,水解部分3-甲基-2-丁烯-1-醇的转化率最高可达63.35%。水解后的料液通过间歇精馏得到纯的3-甲基-2-丁烯-1-醇,最终的3-甲基-2-丁烯-1-醇总收率达到57.4%。A new technology for the preparation of 3-methyl-2-butene-1-ol was investigated based on the hydrolysis of brominated isoamylene and distillation separation technology. By choosing a dipolar solvent,acetonitrile,for the hydrolysis the products showed the highest selectivity. And through further the optimization of experimental operating conditions,hydrolysis yield of 3-methyl-2-butene-1-ol reached 63.35% under the condition of the solvent amount v（acetonitrile）∶v（bromo-3-ene） = 1∶1,hydrolysis temperature 70℃,base amount n（Na OH）∶n（bromo-3-ene） = 1.2∶1 and reaction time 25 minutes. The pure 3-methyl-2-butene-1-ol was made of the feed liquid after hydrolysis by batch distillation operation,and the final total yield of 3-methyl-2-butene-1-ol reached 54%.

关 键 词：溴代异戊烯 3-甲基-2-丁烯-1-醇 水解 精馏 

分 类 号：TQ21[化学工程—有机化工]