Intensification of levofloxacin sono-degradation in a US/H_2O_2 system with Fe_3O_4 magnetic nanoparticles  

磁性纳米Fe_3O_4增强超声/H_2O_2体系降解左氧氟沙星的实验研究(英文)

作　　者：魏红 胡妲 苏洁 李克斌 

机构地区：[1]State Key Laboratory Base of Eco-Hydraulic Engineering in Arid Area, Xi'an University of Technology [2]China Huadian Electric Power Research Institute [3]Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, School of Chemistry and Material Science, Northwest University

出　　处：《Chinese Journal of Chemical Engineering》2015年第1期296-302,共7页中国化学工程学报（英文版）

基　　金：Supported by the National Natural Science Foundation of China(51009115);Shaanxi Provincial Department of Education Key Laboratory Project(13JS067);the Hall of Shaanxi Province Science and Technology(2013JK0881);the Research Plan Project of Water Resources Department of Shaanxi Province(2013slkj-07);the Innovation of Science and Technology Fund of Xi'an University of Technology(211302)

摘　　要：Fe3O4 magnetic nanoparticles(MNPs) were synthesised, characterised, and used as a peroxidase mimetic to accelerate levofloxacin sono-degradation in an ultrasound(US)/H2O2 system. The Fe3O4 MNPs were in nanometre scale with an average diameter of approximately 12 to 18 nm. The introduction of Fe3O4 MNPs increased levofloxacin sono-degradation in the US/H2O2 system. Experimental parameters, such as Fe3O4 MNP dose, initial solution p H, and H2O2 concentration, were investigated by a one-factor-at-a-time approach. The results showed that Fe3O4 MNPs enhanced levofloxacin removal in the p H range from 4.0 to 9.0. Levofloxacin removal ratio increased with Fe3O4 MNP dose up to 1.0 g·L-1and with H2O2 concentration until reaching the maximum. Moreover, three main intermediate compounds were identified by HPLC with electrospray ionisation tandem mass spectrometry, and a possible degradation pathway was proposed. This study suggests that combination of H2O2, Fe3O4 MNPs and US is a good way to improve the degradation efficiency of antibiotics.Fe3O4 magnetic nanoparticles（MNPs） were synthesised, characterised, and used as a peroxidase mimetic to accelerate levofloxacin sono-degradation in an ultrasound（US）/H2O2 system. The Fe3O4 MNPs were in nanometre scale with an average diameter of approximately 12 to 18 nm. The introduction of Fe3O4 MNPs increased levofloxacin sono-degradation in the US/H2O2 system. Experimental parameters, such as Fe3O4 MNP dose, initial solution p H, and H2O2 concentration, were investigated by a one-factor-at-a-time approach. The results showed that Fe3O4 MNPs enhanced levofloxacin removal in the p H range from 4.0 to 9.0. Levofloxacin removal ratio increased with Fe3O4 MNP dose up to 1.0 g·L-1and with H2O2 concentration until reaching the maximum. Moreover, three main intermediate compounds were identified by HPLC with electrospray ionisation tandem mass spectrometry, and a possible degradation pathway was proposed. This study suggests that combination of H2O2, Fe3O4 MNPs and US is a good way to improve the degradation efficiency of antibiotics.

关 键 词：Fe3O4 magnetic nanoparticles H2O2 LEVOFLOXACIN SONOLYSIS HPLC/MS/MS Degradation pathway 

分 类 号：TQ465[化学工程—制药化工]