三维斑点追踪成像评价甲状腺功能亢进患者左心室收缩功能改变的应用价值  

Assessment of left ventricular systolic function in patients with hyperthyroidism by three-dimensional speckle tracking imaging

作　　者：付定虎 田新桥[2] 王珍[1] 吴朝明[3] 潘优津[3] 吕夕明[1] 詹坤高[1] 

机构地区：[1]温州医科大学附属第二医院超声科,温州325027 [2]河南省人民医院超声科 [3]温州医科大学附属第二医院内分泌科,温州325027

出　　处：《浙江医学》2015年第11期967-970,共4页Zhejiang Medical Journal

摘　　要：目的探讨三维斑点追踪成像(3D—STI)技术在评价甲状腺功能亢进(甲亢)患者左心室整体收缩功能中的应用价值。方法选择50例甲状腺功能亢进患者与45例健康志愿者,获取心尖四腔心切面动态图像,存储左心室三维全容积动态图像后,运用3D—STI软件进行脱机分析,得到两组收缩期左心室整体纵向峰值应变(GLS)、圆周峰值应变(GCS)、左心室扭转度角度峰值(LV—tw)、左心室扭力(LV—tor)、左心室心底水平旋转角度峰值(Prot—B)、左心室心尖水平旋转角度峰值(Prot—A)及左心室射血分数(LVEF)等,比较两组三维应变(3DS)指标之间的差异。结果与正常对照组比较,甲亢组的左心室收缩功能增强,GLS、GCS分别为(-20.47±3.08)%vs.(-18.52±4.77)%、(-28.98±3.00)%vs.(-25.88±2.12)%,两组差异均有统计学意义(均P<0.05);甲亢组LV—tw、LV—tor、LVProt—A、LVProt—B均较正常对照组略有增加,但差异均无统计学意义(均P>0.05)。结论 3D—STI可无创、敏感检测甲亢患者左心室三维应变,为临床客观评估甲亢左心室收缩功能提供一种新方法。Objective To assess left ventricular globa sional speckle tracking imaging（3D-STI） echocardiography. systolic function in patients with hyperthyroidism by three-dimen- Methods Fifty patients with hyperthyroidism and 45 healthy volun- teers （control） were studied. The dynamic image of the four-chamber view, three-dimensional imagines of left ventricular were obtained for all individuals, and TomTec 4D LV analysis software was used to calculate the three- dimensional strain （3DS）. The 3DS were measured in all subjects and compared between two groups. Results The LVGLS and LVGCS values in hyperthy- roidism group were significantly higher than those in control group[（-20.47 ±3.08）% vs. （-18.52 ±4.77）% and （-28.98± 3.00）% vs. （-25.88 ± 2.12）%, both P〈0.05]; while there were no significant differences in LV-tw, LV-tor, LVProt-A and LVProt-B be- tween two groups. Conclusion Three-dimensional speckle tracking echocardiography can assess alteration of myocardial global systolic function by measuring 3D-strain in patients with hyperthyroidism.

关 键 词：甲状腺功能亢进 应变 左心室功能 三维斑点追踪成像 

分 类 号：R581.1[医药卫生—内分泌] R445.1[医药卫生—内科学]