甲状腺疾病及其治疗方式与甲状腺相关眼病的关系  

Correlations of thyroid disease and its treatments with thyroid associated ophthalmopathy

作　　者：于园[1] 冯波[1] 

机构地区：[1]同济大学附属东方医院内分泌科,上海200120

出　　处：《中国实用内科杂志》2015年第7期581-583,共3页Chinese Journal of Practical Internal Medicine

摘　　要：甲状腺相关眼病(TAO)是一种累积眼眶的自身免疫性疾病,它与Graves甲状腺功能亢进的关系最为密切,亦可发生于甲状腺功能减退甚至正常甲状腺功能的人群。合并不同甲状腺疾病时TAO临床特点不尽相同。治疗Graves甲亢是治疗TAO的关键之一,通常抗甲状腺药物和甲状腺手术不影响TAO的自然进程,而131I治疗则会导致TAO的发生和进展,但是通过早期干预影响因素如吸烟行为、治疗后甲状腺功能改善、类固醇激素应用等可以改善TAO的转归。Thyroid-associated ophthalmopathy（TAO） is an autoimmune disorder affecting the orbital tissues which generally occurs in patients with hyperthyroidism due to Graves＇ disease, and sometimes it also occurs in patients with hypothyroidism or even euthyroidism but with different clinical features. Undoubtedly the treatment of Graves＇ disease is one of the keys to cure TAO. On average, antithyroid drugs and thyroidectomy do not influence the course of TAO, while radioiodine can influence its development and progression, but the effect can be prevented by intervention of the variables such as smoking, thyroid function and corticosteroids application.

关 键 词：甲状腺相关眼病 甲状腺功能 GRAVES病 13I同位素治疗 

分 类 号：R581[医药卫生—内分泌]