基于α-羟基十二酸经两步可控酯化反应合成单交内酯异辛酯  

Synthesis of Mono-Estolide 2-Ethylhexyl Ester from Alpha-Hydroxyl Dodecanoic Acid by Controllable Two-Step Esterification

作　　者：李荣[1] 方云[1] 胡学一[1] 

机构地区：[1]江南大学化学与材料工程学院食品胶体与生物技术教育部重点实验室,江苏无锡214122

出　　处：《精细化工》2015年第7期806-810,共5页Fine Chemicals

基　　金：国家自然科学基金(21276113)~~

摘　　要：开发了一种从α-羟基脂肪酸经过可控酯化合成单交内酯酯化物的方法,改善从不饱和脂肪酸合成单交内酯这一反应的不可控性。以α-羟基十二酸为原料,与异辛醇酯化合成α-羟基十二酸异辛酯,再与十二酸酯化生成α-十二酰氧基十二酸异辛酯(EHDD);用红外光谱、核磁共振氢谱以及电喷雾质谱表征产物为EN(estolide number)=1,碳原子总数为32的单交内酯异辛酯。实验测得EHDD的熔点为-45.34℃。A controllable synthesis was developed to prepare mono-estolide esters from α-hydroxyl fatty acids in order to improve the uncontrollability of estolide formation from unsaturated fatty acids. 2-Ethylhexyl α-hydroxyl dodecanoate（ EHHD） was prepared in the first step esterification of α-hydroxyl dodecanoic acid with 2-ethylhexanol,and the target product 2-ethylhexyl α-dodecanoyloxy dodecanoate（ EHDD） was synthesized in the second step esterification of EHHD with dodecanoic acid. The products were identified by FTIR,1HNMR and ESI-MS and the final product was verified as an estolide2-ethylhexyl ester with 32 carbon atoms and a character of EN（ estolide number） = 1. The melting point of EHDD is- 45. 34 ℃ measured by DSC method.

关 键 词：α-羟基十二酸 交内酯 单交内酯 交内酯酯化物 酯化反应 油田化学品与油品添加剂 

分 类 号：TQ225.1[化学工程—有机化工]