地塞米松治疗急性一氧化碳中毒后迟发性脑病临床观察  

Clinical observation of dexamethasone on delayed encephalopathy after acute carbon monoxide poisoning

作　　者：陈明玉[1] 李振富[1] 

机构地区：[1]山东省临沂市沂水中心医院,山东临沂276400

出　　处：《中国伤残医学》2015年第14期16-18,共3页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的：观察地塞米松急性一氧化碳中毒后迟发性脑病（ DEACMP）的疗效。方法：将60例DEACMP患者分为2组，对照组患者30例，治疗组患者每组30例。对照组予高压氧、脱水剂、脑保护药物等治疗。治疗组在对照组治疗的基础上加用地塞米松治疗。观察或随访比较治疗效果，并对患者治疗前后蒙特利尔认知评估量表（ MoCA）、简易精神状态评估量表（ MMSE）进行比较。结果：治疗组有效率（93．6％）明显高于对照组（73．3％），2组之间差异有统计学意义（P＜0．05）。治疗后2组患者Mo－CA评分、MMSE评分均上升，上升程度2组比较有统计学差异（P＜0．01）。结论：应用地塞米松治疗DEACMP，疗效显著。Objective：To observe the effect of dexamethasone on delayed encephalopathy （ DEACMP） after acute carbon monoxide poisoning.Methods：60 patients were divided into two groups, treatment group 30 cases and control group 30 cases.Hyperbaric oxygen, dehydrant, cerebral protection drugs were given for control group,dexamethasone was added to therapy group.Compare the treatment effect observed or followed up, and before and after treatment Montreal Cognitive Assessment （ MoCA） , Mini-Mental State Assessment Scale （MMSE） were compared.Results：Efficient （93.6%）, the treatment group was obviously higher than that of control group （73.3%）, the difference between the two groups was statistically significant （P 〈0.05）.After treatment, patients MoCA score, MMSE scores were rising, rising degree of statistical difference between the two groups （P 〈0.01）.Conclusion：Application of dexamethasone in the treat-ment of DEACMP, curative effect should be remarkable.

关 键 词：一氧化碳中毒后迟发性脑病 地塞米松 一氧化碳 

分 类 号：R595.1[医药卫生—内科学]