地塞米松加3%硼酸湿敷与莫匹罗星软膏联用治疗刺激性药物渗漏性损伤患者的临床疗效  

Clinical Efficacy in Patients with Irritant Drug Extravasation Injury by Using Combination of Hydropathic Compress of Dexamethasone and 3% Boric Acid with Mupirocin Ointment

作　　者：卫娜[1] 

机构地区：[1]黄石市普仁医院药剂科,湖北黄石435002

出　　处：《抗感染药学》2015年第3期414-416,共3页Anti-infection Pharmacy

摘　　要：目的:评价3%硼酸加地塞米松湿敷与莫匹罗星软膏联用治疗刺激性药物渗漏性损伤的临床疗效。方法:选取2013年3月—2014年3月间收治的66例刺激性药物渗漏性损伤患者66例作为研究对象,并将其随机分为观察组和对照组各33例;对照组患者给予50%硫酸镁湿敷治疗,观察组患者给予3%硼酸加地塞米松湿敷与莫匹罗星软膏联用治疗,比较两组患者的临床疗效。结果:治疗后观察组患者疼痛程度和肿胀程度均优于对照组,前者治疗总有效率为90.91%,明显高于对照组为69.70%(P<0.05)。结论:对刺激性药物渗漏性损伤患者采用3%硼酸加地塞米松湿敷与莫匹罗星软膏联用治疗的疗效较明显,能有效减轻患者的疼痛感和肿胀程度。Objective： To evaluate the clinical efficacy in patients with irritant drug extravasation injury by using the combination of hydropathic compress of dexamethasone and 3% boric acid with Inupirocin ointment. Methods： The select 66 patients with stimulant medication in patients with extravasation injury as research subjects during March 2013 and March 2014 were randomly divided into two groups, the observing group and the control group（n-33）. The control group was given 50% magnesium still;ate wet treatment and the observation group[n=33） given treatment by us- ing combination of 3% boric acid and dexamethasone with mupirocin ointment. Clinical outcomes were compared. Resulis： The degree of pain and swelling after treatment observation group was lower than that of control group. In addi- tion, the treatment of the observation group total effective rate was 90.91%, significantly higher than that of control group which was 69.70%（P〈0.05）. Conclusion： By using combination of 3% boric acid and dexamethasone with lnupi- rocin ointment, its curative effect is more significant and can effectively reduce the pain and swelling rate the patients.

关 键 词：刺激性药物渗漏性损伤 3%硼酸 地塞米松 莫匹罗星软膏 

分 类 号：R969.3[医药卫生—药理学]