蝙蝠葛碱透皮扩散促渗剂的研究分析  

The research and analysis on Dauricine transdermal penetration enhancers on the research and analysis

作　　者：孙淑波[1] 李冬[1] 时慧[1] 高洪霞[1] 张沙莎[1] 

机构地区：[1]佳木斯大学附属第一医院药剂科,黑龙江佳木斯154003

出　　处：《黑龙江医药科学》2015年第4期70-71,73,共3页Heilongjiang Medicine and Pharmacy

摘　　要：目的:比较、分析、选择蝙蝠葛碱透皮扩散促渗剂。方法:通过改良Franz扩散池,根据Q-t方程和通过考察透皮速率常数,从1%丙二酮,3%Azone,3%OA,十二烷基硫酸钠,冰片,6%尿素,5%松节油中分析比较出最适合蝙蝠葛酚性碱的透皮扩散促渗剂。结果:由实验结果得出3%氮酮为较好透皮渗透促进剂。结论:此研究操作方法简单易行,可重复性好。Objective： To compare,analyzesis,and selection of Dauricine transdermal penetration enhancers.Methods： The most suitable PAMD transdermal diffusion penetration enhancers 5% turpentine was analyzed and compared by modified Franz diffusion cell,the Q- t equation and percutaneous rate constant through the inspection according to the,from 1% C two ketone,3% Azone,3% OA,twelve sodium alkyl sulfate,borneol,6% urea,analysis and comparison of the most suitable PAMD transdermal diffusion penetration enhancers 5% turpentine. Results：Tthe effect of 3% azoneas good transdermal penetration enhancers was good. Conclusion： Tthe research method of operation is simple with,good repeatability.

关 键 词：蝙蝠葛碱 吸收促渗剂 透皮吸收 

分 类 号：R285.1[医药卫生—中药学]