温经汤对子宫内膜异位症大鼠妊娠功能影响的实验研究  

Experimental Study of the Effect of Wenjing Decoction on Pregnancy of Endometriosis Rats

作　　者：马小娜[1] 黄小楼[1] 郝秀芳[1] 王峥[1] 张静 闫军堂[2] 胡兰兰[1] 王国华[1] 

机构地区：[1]北京中医药大学第三附属医院,北京100029 [2]北京中医药大学,北京100029

出　　处：《中医药学报》2015年第3期53-55,共3页Acta Chinese Medicine and Pharmacology

基　　金：北京中医药大学自主选题项目(303-02-07-03-05-02)

摘　　要：目的:观察温经汤对子宫内膜异位症大鼠妊娠率、胚胎大小、胚胎个数的影响,探讨其对子宫内膜异位症大鼠妊娠功能的影响。方法:50只SD大鼠分为空白组,子宫内膜异位症组(模型组),温经汤高剂量组,温经汤低剂量组,达那唑组。结果:1与高剂量组相比:低剂量组的妊娠囊大小明显减小,具有显著性差异(P<0.01);达那唑组的妊娠囊大小明显减小,具有显著性差异(P<0.05);空白组的妊娠囊大小明显减小,具有显著性差异(P<0.01)。2与低剂量组相比:达那唑组的妊娠个数明显减少,具有显著性差异(P<0.05);空白组的妊娠个数明显减少,具有显著性差异(P<0.05);模型组的妊娠个数明显减少,具有显著性差异(P<0.05)。3与空白组相比:温经汤高剂量组的妊娠率明显提高,具有显著性差异(P<0.05)。结论:温经汤对子宫内膜异位症大鼠的妊娠功能有很好的改善作用。Objective：To observe the effects of Wenjing decoction on endometriosis rats, pregnancy rate of embryo size, the number of embryos,this paper discusses the influence of Wenjing decoction for treating endometriosis.Methods：50 SD rats were divided into a blank group, an endometriosis group （ a model group ） , a Wenjing decoction high -dose group,a Wenjing decoction low-dose group and a danazol group.Results：Compared with the high-dose group, the gestational sac size of the low-dose group was significantly reduced, with a significant difference （P〈0.01）;the ges-tational sac size of the danazol group was significantly reduced, with a significant difference （P〈0.05）;the gestational sac size of the blank group was significantly reduced, with a significant difference （P〈0.01）.Compared with Wenjing decoction low-dose group, the pregnancy number of the danazol group was significantly reduced, with a significant difference （ P〈0.05）;the pregnancy number of the blank group was significantly reduced, with a significant difference （P〈0.05）;the pregnancy number of the model group was significantly reduced, with a significant difference （ P〈0.05） .Compared with the blank group,the pregnancy rate of Wenjing decoction high-dose group was significantly re-duced, with a significant difference （P〈0.05）.Conclusion：Wenjing decoction has a very good improving effect on the pregnancy function of endometriosis rat models.

关 键 词：子宫内膜异位症 温经汤 妊娠率 胚胎大小 胚胎个数 

分 类 号：R285.5[医药卫生—中药学]