糖筛查试验异常而糖耐量试验正常孕妇的妊娠结局分析  

Analysis on pregnancy outcomes of abnormal glucose screening test and normal glucose tolerance test in pregnant women

作　　者：李瑞凇 

机构地区：[1]广西壮族自治区桂林市中西医结合医院检验科,541004

出　　处：《检验医学与临床》2015年第13期1871-1872,1875,共3页Laboratory Medicine and Clinic

摘　　要：目的探讨孕期糖筛查试验(GCT)异常而口服葡萄糖耐量试验(OGTT)正常的孕妇对母婴围生期的影响,并观察和分析其妊娠结局,为孕妇孕期保健提供临床客观依据。方法选择该院2012年1月至2014年1月GCT异常而OGTT正常孕妇220例为观察组,另选该院同期240例健康孕妇作为对照组。观察两组孕妇妊娠结局及新生儿状况,并观察新生儿阿普加(Apgar)评分。结果观察组孕妇阴道顺产率61.82%(136/220),低于对照组,观察组剖宫产率为36.36%(80/220),高于对照组,差异均有统计学意义(P<0.05);观察组孕妇产后出血、羊水过多、产褥感染和胎膜早破总计9.55%(21/220),高于对照组(P<0.05)。观察组孕妇巨大儿、早产及新生儿高胆红素血症分别为15.45%(34/220)、5.00%(11/220)和5.45%(12/220),均高于对照组(P<0.05);观察组新生儿平均体质量(3 186.35±31.20)g,高于对照组,观察组新生儿Apgar评分(9.21±0.13)分,低于对照组(P<0.05)。结论 GCT异常而OGTT正常可明显影响孕妇围生期健康,生产时顺产率较低,并发症明显增多,且新生儿早产、巨大儿数量明显增多,易出现高胆红素血症等并发症,影响孕妇和围生期的健康和生命安全,临床实践中应重视GCT异常而OGTT正常的孕妇,及时给予临床干预,有效保障围生期母婴安全。Objective To explore the impact of abnormal glucose challenge test（GCT）and normal oral glucose tolerance test（OGTT）on the maternal and neonatal perinatal period in pregnant women,and to observe and analyze their outcomes to provide the objective basis for pregnancy health care.Methods 220 pregnant women with abnormal GCT and normal OGTT in our hospital from January 2012 to January 2014 were selected as the observation group.Contemporaneous 240 normal pregnant women were selected as the control group.The pregnancy outcomes and neonatal status and Apgar scores were observed in the two groups.Results The vaginal delivery rate of the observation group was 61.82%（136/220）,which was lower than that of the control group,the cesarean section rate of the observation group was 36.36%（80/220）,which was higher than that of the control group（P〈0.05）.The postpartum hemorrhage,polyhydramnios,puerperal infection and premature rupture of membranes in the observation group accounted for 9.55%（21/220）,which was higher than that of the control group（P〈0.05）.The macrosomia,premature delivery and neonatal hyperbilirubinemia of the observation group were 15.45%（34/220）,5.00%（11/220）and 5.45%（12/220）respectively,which were higher than those of the control group（P〈0.05）;the average neonatal body weight mass of the observation group was（3 186.35±31.20）g,which was higher than that of the control group,the neonatal Apgar score of the observation group of was（9.21±0.13）,which was lower than that of the control group（P〈0.05）.Conclusion The abnormal GCT and normal OGTT in pregnant women can significantly affect the perinatal health,has lower natural labor rate and higher complications,moreover the number of premature newborns and macrosomia is significantly increased,easier to develop the complications of hyperbilirubinemia,etc.,which affect the health and life safety of regnant women and perinatal period.Therefore in the clinical practice,pregnant women with abnormal GCT and no

关 键 词：糖筛查试验 口服葡萄糖耐量试验 孕妇 妊娠结局 

分 类 号：R587.1[医药卫生—内分泌]