颌下腺肌上皮癌诊治分析  

Diagnosis and Treatment of Submandibular Myoepithelial Carcinoma

作　　者：刘绍严[1] 倪松[1] 朱一鸣[1] 王健[1] 

机构地区：[1]中国医学科学院肿瘤医院头颈外科,北京100021

出　　处：《中国医刊》2015年第6期28-29,共2页Chinese Journal of Medicine

摘　　要：目的探讨颌下腺肌上皮癌的诊治方法。方法对1999~2013年收治于中国医学科学院肿瘤医院的5例颌下腺肌上皮癌患者进行回顾性分析。结果 5例颌下腺肌上皮癌患者均行手术治疗,其中2例行复发灶扩大切除,部分下颌骨切除,胸大肌瓣修复,3例行局部扩大切除。术后1例死亡,1例失访,3例长期存活。结论根治性手术切除是颌下腺肌上皮癌的主要治疗方式。对于病变广泛或姑息手术的患者,可以考虑辅助放疗,但疗效有待进一步研究证实。Objective To investigate the diagnosis and treatment options of myoepithelial carcinoma derived from submandibular gland. Method From 1999 to 2013, all five cases of submandibular myoepithelial carcinoma, admit-ted to Chinese Academy of Medical Sciences Cancer Hospital, were retrospectively analyzed. Result All five patients underwent surgical treatment. Two cases underwent extended resections of the recurrent lesions and partial resection of the mandible, with reconstruction by pectoralis major muscle flap. The other three underwent local excision. Dur-ing follow-up, one patient died, one was lost, and the other three had long-term survival. Conclusion Radical sur-gery is the main treatment for submandibular gland myoepithelial carcinoma. For locally advanced lesions or pallia-tive options,adjuvant radiotherapy may be considered,but the effects are yet to be confirmed by further studies.

关 键 词：肌上皮癌 颌下腺 根治性手术 放射疗法 

分 类 号：R651[医药卫生—外科学]