电感耦合等离子体质谱法测定痕量铁元素时碰撞反应池条件的探讨  

Discussion on collision/reaction cell conditions for determination of trace iron by inductively coupled plasma mass spectrometry

作　　者：王征[1] 赵学玒[1,2] 孙传强[1] 汪曣[1,2] 

机构地区：[1]天津大学精密仪器与光电子工程学院,天津300072 [2]天津市生物医学检测技术与仪器重点实验室,天津300072

出　　处：《冶金分析》2015年第6期1-7,共7页Metallurgical Analysis

基　　金：2011科技部重大科学仪器设备开发专项(2011YQ14014702);2013国家863计划项目(2014AA022305);2013教育部高等学校博士学科点科研基金项目(20130032110057)

摘　　要：电感耦合等离子体质谱法(ICP-MS)在测量痕量铁元素时会受到ArO+多原子离子的严重干扰,碰撞/反应池技术可以有效的去除该干扰。通过对碰撞/反应池工作参数进行探讨,以提高ICP-MS检测铁元素的能力。讨论了NH3、He、H2、N2O以及He-H2和He-NH3混合气6种四极杆碰撞/反应池气体类型及流速、碰撞/反应池RPq值、碰撞/反应池偏置电压(CRO)及四极杆质量分析器偏置电压(QRO)对ArO+干扰去除效果的影响,获得了优化的碰撞/反应池参数。实验表明:0.3mL/min NH3-1.3mL/min He混合气条件下得到的铁元素检出限最低;在不同的气体条件下RPq优化值为0.5;CRO及QRO在碰撞模式下优化值分别为-17V、-7V,在反应模式及混合气模式下分别为-1V、-11V;在优化条件下铁元素的检出限为14ng/L。The determination of trace iron by inductively coupled plasma mass spectrometry（ICP-MS）was seriously interfered by polyatomic ion ArO＋.Such interference could be effectively eliminated by the collision/reaction cell technology.In this paper,the working parameters of collision/reaction cell were investigated to improve the detection ablity of iron by ICP-MS.The effect of several experimental factors on the elimination of ArO＋interference was discussed,including six types of quadrupole collision/reaction cell gases（NH3,He,H2,N2 O,He-H2 and He-NH3）,the flow rate of gas,the collision/reaction cell RPq value,the collision/reaction cell offset（CRO）and quadrupole mass analyzer rod offset（QRO）.The optimal parameters of collision/reaction cell were obtained.The experimental results indicated that the detection limit of iron was lowest when 0.3mL/min NH3-1.3mL/min He mixed gas was selected as the collision/reaction cell gas.The optimized RPq value was 0.5under different gas conditions.The optimized value of CRO and QRO under collision mode were-17Vand-7V,respectively,and they were-1V and-11 Vrespectively both under reaction mode and mixed gas mode.The detection limit of iron under optimized conditions was 14ng/L.

关 键 词：电感耦合等离子体质谱法(ICP-MS) 碰撞/反应池 痕量 铁 

分 类 号：O657.63[理学—分析化学]