强化随访对非瓣膜病心房颤动服用华法林患者抗凝效果的影响  

Impact of intensive follow-up visit on Warfarin anticoagulant in patient with nonvalvular atrial fibrillation

作　　者：朱佩兰[1] 林丽跃[1] 胡平浪[2] 崔丽丽[1] 黄周青[1] 李海鹰[1] 王美兰[1] 

机构地区：[1]温州医科大学附属第一医院心内科,325000 [2]温州医科大学附属第一医院神经内科,325000

出　　处：《中华现代护理杂志》2015年第17期1993-1995,共3页Chinese Journal of Modern Nursing

基　　金：浙江省温州市科技局立项课题（Y20130018）

摘　　要：目的：探讨非瓣膜病心房颤动患者服用华法林抗凝治疗过程中强化随访的方式对抗凝效果的影响。方法选择非瓣膜病的持续性心房颤动患者100例,按计算机产生随机数随机分成强化随访组和常规随访组,每组50例。比较两组患者6个月中的治疗依从性情况、INR值以及栓塞、出血事件。结果强化随访组患者服药后6个月INR的达标率为86.0%,常规随访组为72.0%,两组比较差异有统计学意义（χ^2=4.570,P〈0.05）；在出血发生率方面,强化随访组为12%,常规随访组为28%,差异有统计学意义（χ^2=4.000,P〈0.05）。结论强化随访对患者起到宣教、督促、提醒的作用,使服用华法林的患者得到规范有效的抗凝治疗,提高了用药的安全性,从而达到预防脑卒中的效果。Objective To explore the impact of intensive follow-up visit in patients with nonvalvular atrial fibrillation taking Warfarin in process of anticoagulant therapy. Methods A total of 100 patients with persistent nonvalvular atrial fibrillation were randomly divided them into intensive follow-up group and regular follow-up group on average. We compared the treatment compliance, INR value, embolism and hemorrhage between two groups. Results The INR qualified rate was 86. 0% after 6 months taking medication in the intensive follow-up group and 72. 0% in the regular follow-up group （χ^2 =4. 570,P〈0. 05）. The incidence rate of hemorrhage was 12% in the intensive follow-up group and 28% in the regular follow-up group （χ^2 =4. 000,P〈0. 05）. Conclusions With the function of propaganda, education, supervision, promotion and attention on patients, follow-up visit makes patients taking Warfarin receive normative, effective anticoagulant treatment and improves the safety of medicine use, thus the effect of preventing stroke can be achieved.

关 键 词：心房颤动 强化随访 抗凝治疗 华法林 

分 类 号：R541.75[医药卫生—心血管疾病]