选区激光熔化TC4生物腐蚀和生物相容性分析  

Study on biological corrosion and biocompatibility of TC4 alloy by selective laser melting

作　　者：王勇[1] 蒋军杰 乔丽英[1] 胡东[1] 李忠华[2] 李梦华[3] 陈艺韬 

机构地区：[1]重庆大学材料科学与工程学院,重庆400044 [2]重庆大学机械工程学院,重庆400044 [3]重庆大学生物工程学院,重庆400044

出　　处：《重庆大学学报（自然科学版）》2015年第3期21-27,共7页Journal of Chongqing University

基　　金：重庆市应用开发计划重大项目(cstc2014yykfc50002);中央高校基金项目(CDJZR12110072);国家自然科学基金资助项目(51101174);重庆市自然科学基金资助项目(cstc2011jjA50008)~~

摘　　要：选区激光熔化(SLM)为降低TC4钛合金医用植入体的弹性模量、减小应力屏蔽效应提供了一种有效的解决方案,但这种材料在投入实际应用前尚需有充分的生物安全性评价。采用SLM技术制备出致密度为99.5%的TC4合金,通过电化学实验、溶血实验和细胞毒性实验测试了SLM成形TC4的生物腐蚀性能和生物相容性,并与传统铸轧工艺制备的合金进行了对比。实验结果表明:前者相比于后者有着更好的耐蚀性能,并且SLM成形TC4还具有优良的生物相容性,在生物医用植入物方面展现出很好的应用前景。Selective laser melting（SLM）,a kind of layer by layer processing technology,has significant performance advantages on preparation of porous materials.SLM provides an effective method to reduce the elastic modulus and the stress shielding effect of TC4 titanium alloys for medical implants.However,there is still no convincing biological safety evaluation before practical application.In this paper,TC4 alloy with a relative density of 99.5%is prepared in the adoption of SLM.We examine corrosion resistance and biocompatibility for TC4 alloy prepared by SLM via electrochemical,hemolysis and cytotoxicity test.Comparison between TC4 alloy prepared by SLM and traditional cast rolling process is discussed.The results show that TC4 alloy prepared by SLM has better corrosion resistance and more excellent biocompatibility than traditional process,and it has tremendous application in futures on biomedical implants.

关 键 词：选区激光熔化 TC4 腐蚀性能 生物相容性 

分 类 号：TG146[一般工业技术—材料科学与工程]