特殊染色对犬恶性纤维组织细胞瘤的鉴别诊断  

Differential Diagnosis of Canine Malignant Fibrous Histiocytoma by Special Staining

作　　者：李瑞珍[1] 韩庆功[1] 梁莹莹[1] 郝军红[1] 赵俊江 潘耀谦[1] 

机构地区：[1]河南科技学院动物科学学院,河南新乡453003

出　　处：《河南农业科学》2015年第7期139-142,152,共5页Journal of Henan Agricultural Sciences

基　　金：河南省科技攻关项目(132102110118);河南科技学院人才科学研究基金项目(2009001)

摘　　要：为鉴别犬恶性纤维组织细胞瘤的细胞成分,通过临床检查、肿瘤切除、石蜡切片、组织切片的普通染色和特殊染色等方法对犬恶性纤维组织细胞瘤的形态结构进行了研究。结果显示,犬恶性纤维组织细胞瘤多呈浸润性生长,累及多种组织和器官。肿瘤的体积大,无完整的包膜,表面有大小不一的结节,色泽多样,呈淡红色、灰白色、棕色和黑红色。镜检,大部分肿瘤结节以组织细胞为主,并见由其演变而来的泡沫样细胞和含铁细胞。肿瘤细胞多以索状和席片状排列为主,间质成分较少。少数结节是以纤维细胞为主,肿瘤细胞多以网状和旋涡状排列,间质较多,形成明显的小叶结构,其中常浸润有较多的淋巴细胞。综上,犬恶性纤维组织细胞瘤是一种多细胞性肿瘤,其恶性程度与肿瘤的细胞成分有关,以组织细胞为主的肿瘤,其恶性程度比以纤维细胞为主的高。To identify the cellular constituent of canine malignant fibrous histiocytoma （CMFH）, morphologic structures of tumor were investigated by clinic examination,tumor resection,paraffin section and staining section with common staining and special staining methods. The results demonstrated that CMFH showed infiltrative growth and involved several tissues and organs. The dimension of tumor was bigger and no completely envelope was seen. There were lots of nodes with pink, grey white, brown and black red, on the tumor surface. Microscopically, the most tumor nodules were mainly composed of histioeytes, and a number of foam cells and siderophores were developed from histiocytes. The arrangement of tumor cells showed mainly cord-liking and platy-liking. The mesenehyma was less in tumor tissues. A few nodules were primarily consisted of fibrous ceils. The arrangement of tumor cells looked like nets and swirl. The mesenehyma was more and formed evident lobule. A few lymphocytes infiltrated in lobular mesenchyma. In conclusion, CMFH was one of muhicellularity tumor, its grad malignancy of fibrous histiocytoma mainly related to component of tumor cell and the tumor consisted of histiocytes was more malignant than one composed of fibrous cells.

关 键 词：犬 恶性纤维组织细胞瘤 特殊染色 鉴别诊断 

分 类 号：S685[农业科学—观赏园艺]