尿毒症患者肺部感染的危险因素分析  

Risk factors for pulmonary infections in patients with uremia

作　　者：卢蓉[1] 刘俊峰 金威[1] 周国勇[3] 刘颖[1] 

机构地区：[1]华中科技大学医院内科 [2]江汉大学附属医院肾内科 [3]江汉大学

出　　处：《中华医院感染学杂志》2015年第14期3226-3228,共3页Chinese Journal of Nosocomiology

基　　金：湖北省科技厅计划基金资助项目(HB20130006D)

摘　　要：目的探讨尿毒症患者发生肺部感染的危险因素,达到早期预防目的。方法选取2012年3月-2014年9月接受治疗的63例尿毒症发生肺部感染患者作为观察组,另选取同时期接受治疗的50例无肺部感染的尿毒症患者作为对照组,回顾性分析两组患者血清白蛋白、球蛋白、血红蛋白、C-反应蛋白和血清肌酐含量,统计分析两组患者住院时间。结果观察组患者血清白蛋白和血红蛋白含量显著低于对照组患者,观察组患者营养状况较差,感染严重,与对照组比较差异有统计学意义(P<0.05);观察组患者C-反应蛋白及血清肌酐迅速上升,住院时间较长,明显高于对照组患者,两组比较差异有统计学意义(P<0.05);观察组患者随着年龄增大,感染率也随之升高,组间比较差异有统计学意义(P<0.05)。结论随着年龄增长、肾脏功能减弱、营养状况不良和住院时间过长等,是引起尿毒症患者并发肺部感染的高危因素,及早做好相关预防工作,有利于患者病情恢复。OBJECTIVE To explore the risk factors for pulmonary infections in the patients with uremia so as to meet the purpose of early prevention.METHODS Totally 63 uremia patients with pulmonary infections who were treated from Mar 2012 to Sep 2014 were chosen as the observation group,meanwhile,50 uremia patients without pulmonary infections who were treated during the same period were set as the control group.The contents of serum albumin,globulin,hemoglobin,C-reactive protein,and serum creatinine were determined;the length of hospital stay was statistically analyzed.RESULTS The contents of serum albumin and hemoglobin of the observation group were significantly lower than those of the control group.The nutrition status was poorer and the infection was more severer in the observation group,as compared with the control group,the difference was significant（P〈0.05）.The levels of C-reactive protein and creatinine of the observation group were increasingly elevated,the length of hospital stay of the observation group was significantly longer than that of the control group（P〈0.05）.The infection rate of the observation group was increased with the age,and the difference was significant（P〈0.05）.CONCLUSIONThe high risk factors for the pulmonary infections in the uremia patients include the increase of age,renal dysfunction,malnutrition,and prolonged length of hospital stay.The corresponding prevention measures may facilitate the rehabilitation of the patients.

关 键 词：尿毒症 肺部感染 危险因素 相关性 

分 类 号：R563.1[医药卫生—呼吸系统]