升气壮阳方联合标准化屋尘螨疫苗免疫治疗儿童变应性哮喘的临床疗效及安全性评价  

Sheng-qi-zhuang-yang formula combined with specific immunotherapy with standardized house dust mite vaccine on allergic asthmatic children : A preliminary effect and safety assessment

作　　者：郑燕霞[1] 刘卓勋[1] 李冰洁[2] 江文文[1] 许尤佳[1] 

机构地区：[1]广东省中医院,广州市510120 [2]中国南方航空股份有限公司航空卫生中心,广州市510406

出　　处：《实用医学杂志》2015年第11期1855-1858,共4页The Journal of Practical Medicine

基　　金：广东省中医院中医药科学技术研究专项资助(编号:YK2013B2N18)

摘　　要：目的:评价升气壮阳方联合标准化屋尘螨疫苗免疫治疗儿童变应性哮喘的临床和安全性。方法:2011年1月至2013年12月将来自广东省中医院接受标准化屋尘螨疫苗免疫治疗的轻至中度变应性哮喘患儿100例分为治疗组与对照组,治疗组加用升气壮阳方,对照组单纯应用免疫治疗,从哮喘症状的缓解、呼吸功能的改善、不良反应的发生等三方面进行观察。结果:脱敏治疗的显效时间有所提前。在呼吸功能、不良反应方面,与对照组没有差别。结论:治疗组升气壮阳方联合标准化屋尘螨免疫治疗儿童哮喘在临床显效方面具有优势,且并未增加不良反应的发生,值得进一步临床试验。Objective To evaluate the efficacy and safety of Sheng-qi-zhuang-yang formula combined with specific immunotherapy （SIT） with standardized house dust mite vaccine on allergic asthmatic children. Methods Participants were 100 children with mild to moderate allergic asthma, who were receiving SIT at Guangdong Provincial Hospital of Chinese Medicine from Jan 2011 to Dec 2013, who were divided into treatment group and control group. Patients in the treatment group received Sheng-qi-zhuang-yang Decoction combined with SIT while patients in the control group received SIT alone. Asthma symptom scores, respiratory function and related adverse events were compared before and after treatment, between groups. Results The desensitization treatment functions was ahead of time than expected in both groups. There is no significant difference between groups in terms of respiratory function and adverse effects. Conclusion Sheng-qi-zhuang-yang decoction combined with SIT for allergic asthmatic children seems to advance clinical effect without increasing adverse events. Further large scale clinical trial is required to confirm this.

关 键 词：变应性哮喘 升气壮阳方 儿童 屋尘螨 免疫治疗 

分 类 号：R725.6[医药卫生—儿科]