不同剂量氨溴索对肺叶切除术后并发症的影响  

Effect of ambroxol with different doses on postoperative complications of pulmonary lobectomy

作　　者：黄庆[1,2] 劳永光[1,2] 张志辉[1,2] 

机构地区：[1]广东省湛江中心人民医院外科ICU,广东湛江524037 [2]广东省湛江中心人民医院心胸外科,广东湛江524037

出　　处：《广东医学院学报》2015年第1期103-105,共3页Journal of Guangdong Medical College

摘　　要：目的比较不同剂量氨溴索对肺癌患者肺叶切除术后并发症、住院时间及费用的影响。方法 100例因肺癌行肺叶切除术患者随机分为A、B两组,每组50例。手术当天及术后3 d,在常规治疗基础上,A组加入大剂量(1 005mg/d)氨溴索静脉滴注,B组予常规剂量(90 mg/d)氨溴索静脉推注。比较两组术后并发症、住院时间及费用。结果 A组的术后肺部并发症、住院时间和住院费用明显低于与B组(P<0.01或0.05)。结论大剂量氨溴索治疗可减少肺叶切除术后并发症、缩短住院天数、减轻经济负担。Objective To compare the effect of ambroxol with different doses on postoperative complications, hospitalization and cost in patients with lung cancer underwent pulmonary lobectomy. Methods One hundred patients with lung cancer underwent pulmonary lobectomy were randomly divided into Groups A and B. Based on conventional therapy, Group A（n=50） and Group B（n=50） were treated with high（1 005 mg/d） and low（90 mg/d） doses of ambroxol, respectively. Postoperative complications, hospitalization and expenditure were compared in both groups. Results The postoperative pulmonary complications, hospitalization and cost were lower in Group A than in Group B（P〈0.01 or 0.05）. Conclusion High dose of ambroxol treatment can decrease postoperative complications, hospitalization and economic burden in patients with pulmonary lobectomy.

关 键 词：肺叶切除术 并发症 氨溴索 

分 类 号：R655.3[医药卫生—外科学]