北京市丰台区健康人群麻疹抗体水平监测  

Monitoring of Measles Antibody Level in Healthy Population in Fengtai District of Beijing

作　　者：毛雯雯[1] 王中战[1] 

机构地区：[1]丰台区疾病预防控制中心,北京100071

出　　处：《现代预防医学》2015年第14期2636-2638,共3页Modern Preventive Medicine

摘　　要：目的了解丰台区不同健康人群的麻疹免疫水平,以制定相应疫苗免疫策略。方法采用随机抽样方法抽取10个行政村/居共计220名健康人群调查人口学信息和免疫史,采用酶联免疫吸附试验检测麻疹Ig G抗体。结果丰台区健康人群麻疹抗体总阳性率和平均抗体浓度分别为86.8%和2 089.94 IU/L,不同年龄组间、不同免疫史人群、不同职业人群的麻疹抗体阳性率和平均抗体浓度均有统计学差异,χ2值分别为84.897,61.5,25.122,P<0.001;F值分别为22.308,42.1,4.576,P<0.001。结论在提高常规免疫及时性的基础上,大年龄组人群麻疹疫苗接种应覆盖到本市户籍,尤其对育龄妇女、干部职员等一些重点人群加强宣教,开展强化免疫活动,以达到减少易感人群,控制麻疹疫情的目标。Objective This work was to monitor measles antibody level in the healthy population in Fengtai district of Beijing. Methods Random sampling method was used to collect demographic data and immunity history data of 220 healthy people from 10 village or urban communities for epidemiologieal investigation. Quantitative enzyme-linked immunosorbent assay （ELISA） was used to test the measles antibody IgG level. Results The general positive rate of measles antibody in healthy population was 86.8% and the average concentration of antibody was 2089.94IU/L. The measles antibody positive rate and average concentration differed significantly with age, immunity history and occupation. Conclusion Apart from timely children routine immunization, it is necessary to expand the immunization to all registered residents of this district, with emphasis on women of childbearing age and officials, so as to reduce the susceptible population and control measles epidemic.

关 键 词：健康人群 麻疹 抗体 

分 类 号：R183.3[医药卫生—流行病学] R181.36[医药卫生—公共卫生与预防医学]