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出 处:《中国药房》2015年第20期2804-2806,共3页China Pharmacy
基 金:重庆市卫生局中医药科研计划立项(No.ZY20132159)
摘 要:目的:观察蓝红光联合中医外治法治疗臁疮的临床疗效和不良反应。方法:将64例臁疮患者按随机数字表法分为试验组和对照组,各32例。两组患者均行静脉滴注灯盏细辛注射液及参芎葡萄糖注射液以改善患肢微循环,在此基础上,试验组采用蓝红光(蓝光照射20 min+红光照射10 min)联用中医外治法,每日1次;对照组只采用中医外治法,每日1次。治疗1个月后,观察并比较两组患者的临床疗效和臁疮愈合时间,并监测不良反应。结果:试验组治愈率为78.13%,总有效率为96.88%,均高于对照组(分别为40.63%、81.25%),差异有统计学意义(P<0.05)。试验组臁疮愈合时间平均为(18.75±5.97)d,对照组为(27.12±6.67)d,两组比较差异有统计学意义(P<0.05)。治疗期间两组患者均未见不良反应发生。结论:蓝红光联合中医外治法治疗臁疮疗效好、安全性高,并能缩短臁疮的愈合时间。OBJECTIVE: To observe clinical efficacy and ADR of blue and red light phototherapy combined with TCM exter- nal treatment in the treatment of ecthyma. METHODS: 64 ecthyma patients were randomly divided into experimental group and control group by number with 32 cases in each group. Both groups were provided with intravenous drip of Erigeron injection and Shenxiong glucose injection to improve limb microcirculation. The experimental group was also provided with blue and red light phototherapy (blue light 20 min± red light 20 min) combined with TCM external treatment once a day; while control group was provided with only TCM external treatment once a day. After 1 month treatment, clinical efficacy and healing time of 2 groups were observed and compared, and ADR monitoring was conducted. RESULTS: The cure rate of experimental group was 78.13%, and the total effective rate was 96.88%, which were higher than those of control group (40.63% and 81.25% ), there was statisti- cally significant difference (P〈0.05). The average healing time of experimental group was (18.75 ± 5.97) d, and that of control group was (27.12 ± 6.67)d; there was statistically significant difference between 2 groups (P〈0.05). No ADR was found in 2 groups during treatment. CONCLUSIONS: Blue and red light phototherapy combined with TCM external treatment in the treatment of ecthyma has the remarkable curative effect and good safety, and shorten the healing time.
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