经皮房间隔缺损封堵术后即时肺血管阻力的变化  

Change of pulmonary vascular resistance immediately after transcatheter closure of atrial septal defects

作　　者：林晓程 费洪文[2] 林琼雯[2] 李贺智[2] 

机构地区：[1]汕头大学医学院,广东汕头515031 [2]广东省人民医院(广东省医学科学院),广州510080

出　　处：《岭南心血管病杂志》2015年第3期338-339,364,共3页South China Journal of Cardiovascular Diseases

摘　　要：目的探讨右心导管术评价经皮房间隔封堵术后即时肺血管阻力变化。方法选取2013年2月至2014年4月在广东省人民医院确诊为继发孔型房间隔缺损并行经皮房间隔缺损封堵术的患者28例,记录封堵前和封堵后30 min内经导管测定的肺总阻力及肺小动脉阻力并进行比较。结果28例房间隔缺损患者封堵成功率100%;术后均无残余左向右分流。房间隔缺损封堵术后即刻肺总阻力和肺小动脉阻力均比术前增高,差异有统计学意义[肺总阻力:(4.37±1.94)Wood vs.(2.75±1.97)Wood,P<0.01;肺小动脉阻力:(2.60±1.93)Wood vs.(1.81±1.73)Wood,P<0.01]。结论房间隔缺损患者行经皮房间隔缺损封堵术后即时肺血管阻力较术前增高。Objectives To evaluate the value of right heart catheterization on the change of pulmonary vascular resistance immediately after transcatheter closure of atrial septal defects. Methods From February 2013 to April 2014,28 cases were diagnosed as secundum atrial septal defect and received transcatheter closure in Guangdong General Hospital. Total pulmonary resistance and pulmonary arteriolar resistance were recorded and compared in these cases before surgery and within 30 minutes after surgery. Results Success rate of operation was 100%. There was no postoperative residual left-to-right shunt. Total pulmonary resistance and pulmonary arteriolar resistance were significantly higher within 30 minutes after surgery [total pulmonary resistance ：（4.37 ±1.94） Wood vs.（2.75 ±1.97）Wood, P〈0.01; pulmonary arteriolar resistance ：（2.60±1.93） Wood vs.（1.81±1.73） Wood, P〈0.01 ]. Conclusions Pulmonary vascular resistance increases within a short time after transcatheter closure of congenital atrial septal defects.

关 键 词：房间隔缺损 封堵术 右心导管术 肺血管阻力 

分 类 号：R541.1[医药卫生—心血管疾病]