2014年深圳市出口加工区健康人群登革热抗体水平分析  

Analysis on the antibody level of dengue virus among the healthy people in Shenzhen Export Processing Zone in 2014

作　　者：何志明 吴能简 吴崧霖 严共旭 王德全[2] 

机构地区：[1]深圳市坪山新区疾病预防控制中心,广东深圳518118 [2]广东药学院,广东省分子流行病学重点实验室

出　　处：《实用预防医学》2015年第8期947-949,共3页Practical Preventive Medicine

基　　金：深圳市医疗卫生类科研资助项目(201302230);深圳市坪山新区医疗卫生发展孵化资助项目(201308)

摘　　要：目的了解深圳市出口加工区健康人群登革热抗体水平，为制定登革热防治对策提供依据。方法2014年10月，在深圳市出口加工区随机抽取17～60岁健康人群508人进行血清登革热病毒IgG抗体水平检测。结果检测508人中，登革病毒IgG抗体阳性的14人，阳性率为2．76％。登革病毒IgG抗体阳性率，男性为2．15％，女性为5．56％，男女比较差异无统计学意义（x2=3．19，P〉0．05）；17-25岁阳性率为2．61％，26--35岁为2．23％，36--60岁为3．55％，各年龄组比较差异无统计学意义（x2=0．64，P〉0．05）。不同职业和文化程度间登革病毒IgG抗体阳性率差异也均无统计学意义。结论深圳市出口加工区及周边片区健康人群中登革病毒抗体阳性率较低，提示一旦存在输入传染源，则有登革热暴发疫情的可能。建议积极开展预防登革热的宣传教育，加强登革疫情和媒介监测，完善登革热防控体系。Objective To investigate the antibody level of dengue virus among the healthy people in Shenzhen Export Process- ing Zone so as to provide evidence for formulating the strategy of dengue fever prevention and control. Methods Serum IgG antibody to dengue virus was detected in 508 healthy people aged 17 to 60 years in Sbenzben Export Processing Zone in Octobex, 2014. Results A total of 508 healthy people were tested, with the antibody positive rate of 2.76% （14/508）. The antibody positive rates of males and females were 2.1596 and 5.5696 respectively, no statistically significant difference was found between the genders （X2 = 3.19, P 〉0.05）. The antibody positive rates of the groups of 17 - 25, 26 - 35 and 36 - 60 years old were 2.61%, 2.23 % and 3.55 % respectively, no statistically significant differences were found among the groups with different ages （2 = 0.64, P 〉0.05）. No statistically significant difference was found in the positive rate of dengue virus antibody IgG among people with different occupations and educational backgrounds. Conclusions The positive rate of dengue virus antibody IgG is low among healthy people in Shenzhen Export Processing Zone and the surrounding area. It suggests the possibility of dengue fever outbreak if there is the source of infection. It is necessary to carry out public health education about dengue prevention, strengthen the surveillance on outbreak and vector of dengue fever and improve the prevention and control system for dengue fever.

关 键 词：登革热 酶联免疫吸附测定 健康人群 

分 类 号：R512.8[医药卫生—内科学]