益母妇宁胶囊中苦参碱、氧化苦参碱的含量测定  

Determination of Matrine and Oxymatrine in Yimufuning Capsules

作　　者：周俊 彭翠香[2] 范茜茜[2] 葛庆[2] 吴宁 顾承刚 许汉林[2] 

机构地区：[1]三峡食品药品检验检测中心,湖北宜昌443005 [2]湖北中医药大学药学院,湖北武汉430065 [3]武汉药谷科技开发有限公司,湖北武汉430075

出　　处：《湖北中医药大学学报》2015年第3期32-35,共4页Journal of Hubei University of Chinese Medicine

基　　金：中药新药临床批件(CX2L1100045)

摘　　要：目的建立益母妇宁胶囊中苦参的含量测定方法,为其质量控制提供依据。方法采用高效液相色谱法(HPLC)对方中苦参的有效成分苦参碱、氧化苦参碱进行含量测定。结果测得本品中苦参碱、氧化苦参碱的总含量为10.53mg/g。结论本方法可以准确地进行定量分析,可用于益母妇宁胶囊的质量控制。Objective To establish the method of the content determination of Yimufuning capsules and provide a basis of quality con -trol.Methods The content of Matrine and Oxymatrine was determined by HPLC .Result The total content of the Matrine and Oxymatrine in this product is 10.53mg/g.Conclusion The methed is accurate ,reliable and available with promising reproducibility and can be used in controlling the quality of Yimufuning capsules .

关 键 词：益母妇宁胶囊 苦参碱 氧化苦参碱 含量测定 

分 类 号：R284[医药卫生—中药学]