转录组测序技术在绒毛用羊中的应用研究进展  

Application Research Progress on Transcriptome Sequencing Technology in Wool Sheep and Cashmere Goat

作　　者：李晓燕[1] 王晓铄[2] 王乐乐[1] 张燕军[1] 苏蕊[1] 王瑞军[1] 李金泉[1] 

机构地区：[1]内蒙古农业大学动物科学学院,呼和浩特010018 [2]内蒙古农业大学动物遗传育种与繁殖重点实验室,呼和浩特010018

出　　处：《中国畜牧兽医》2015年第7期1692-1698,共7页China Animal Husbandry & Veterinary Medicine

基　　金：国家自然科学基金(31260539);内蒙古农业大学优秀青年科学基金(2014XYQ-1);国家高技术研究发展计划项目863计划(2013AA102506);国家农业部现代农业产业技术体系(CARS-40-05)

摘　　要：高通量转录组测序技术在绒毛用羊参考转录组信息的研究过程中发挥着越来越重要的作用。作者主要介绍采用二代高通量测序技术(以RNA-Seq为主),挖掘绒毛用羊产毛、产绒等重要功能性状的分子标记,重点分析新发现的山羊新基因及与绒毛用性能相关的候选标记,为调控绒毛生长的分子机制、相关基因表达调控网络及绒毛分子育种等工作的深入研究提供参考。High-throughput sequencing technology plays an increasingly important role in the process of transcriptome information researching with wool sheep and cashmere goat. By using the next-generation high-throughput sequencing （NGS） technology （based on RNA-Seq）,the molec- ular markers of important functional traits of wool-yield and cashmere-producing were explored. Novel genes and candidate markers related with cashmere goat performance were highly focused, which providing the reference for the further study of regulation molecular mechanism of cash- mere growth,the network of gene expression regulation and molecular breeding in cashmere and WOO1.

关 键 词：转录组 测序技术 绒毛用羊 

分 类 号：S813.3[农业科学—畜牧学]