异丙酚复合芬太尼在靶控静脉麻醉与静吸复合麻醉的疗效比较  

A Comparative Study on the Efficacy of Propofol-fentanyl in Target-controlled Intravenous Anesthesia and Intravenous Inhalational Anesthesia

作　　者：刘奕君[1] 莫桂熙[1] 蔡伟华[1] 

机构地区：[1]广东医学院附属医院麻醉科,广东广州524001

出　　处：《现代诊断与治疗》2015年第6期1203-1205,共3页Modern Diagnosis and Treatment

摘　　要：目的 探析手术患者进行异丙酚复合芬太尼靶控静脉麻醉与静吸复合麻醉的临床效果比较。方法 入选我院2013年8月~2014年8月手术患者80例,按随机数字表法分为观察组、对照组,每组40例,观察组予以芬太尼复合异丙酚靶控静脉麻醉,对照组予以芬太尼、异丙酚复合七氟醚静吸复合麻醉,比较2组的麻醉效果;比较2组拔管后1h、拔管后3h的OAAS评分、VAS评分;比较两组术后恢复呼吸时间、恢复定向力时间、拔管时间。结果 观察组、对照组的麻醉有效率分别为92.5%、72.5%,差异有统计学意义（P〈0.05）;观察组拔管后1h、拔管后3h的OAAS评分、VAS评分显著优于对照组,差异有统计学意义（P〈0.05）;观察组的术后恢复呼吸时间、恢复定向力时间、拔管时间等指标显著优于对照组,差异有统计学意义（P〈0.05）。结论 芬太尼复合异丙酚靶控麻醉效果确切,可作为外科手术的首选麻醉方法,值得临床推广。Objective To compare the clinical effects of propofol-fentanyl in targetvcontrolled in-travenous anesthesia and intravenous inhalational anesthesia on surgical patients through explo-ration and analysis. Methods 80 surgical patients in our hospital from August 2013 to August 2014 were divided into to the observation group and the control group by the method of random number table,40 patients in each group.The observation group was treated with propofol-fentanyl target-controlled intravenous anes-thesia while the control group was treated with propofol-fentanyl and sevoflurane intravenous inhalation-al anesthesia.The anesthetic effects of two groups were compared.The OAAS scores and VAS scores at 1h and 3h after extubation were compared be-tween two groups.The duration from the termination of the surgery to full recovery of spontaneous breathing, orientation,and extubation were compared between two groups. Results The effective rates of anesthesia of the observation group and the control group were respectively 92.5% and 72.5%, and the difference was of statistical significance （P〈0.05）. The OAAS scores and VAS scores of the observation group were significantly better than those of the control group at 1h and 3h after extubation, and the difference was of statistical significance （P〈0.05）. The indexes of the observation group including the duration from the termination of the surgery to full recovery of spontaneous breathing, orientation,and extubation were significantly better than those of the control group, and the difference was of statistical significance （P〈0.05）. Conclusions The anesthetic ef-fects of propofol-fentanyl in target-controlled anesthesia are remarkable and this method can be regarded as a priority in surgeries,thus worth clinical expansion.

关 键 词：麻醉效果 丙泊酚 外科手术 芬太尼 

分 类 号：R614.2[医药卫生—麻醉学]