自制黄连膏对烧伤患者的临床疗效及对血液流变学的影响分析  

Clinical Effect of Using Self-made Coptis Ointment on Treating Burned Patients and Impact Analysis of its Hemorheology

作　　者：陈静[1] 吕国忠[2] 

机构地区：[1]南京中医药大学,江苏南京210000 [2]无锡市第三人民医院,江苏无锡214000

出　　处：《四川中医》2015年第6期56-59,共4页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:探讨采用自制黄连膏治疗烧伤患者对患者血瘀证的影响作用。方法:自2013年1月至2014年12月本院烧伤整形外科共收治早期烧伤患者82例,采用随机数字表法分为常规治疗组和中药组各41例,常规治疗组采用烧伤常规疗法,中药组加用自制黄连膏治疗,比较两组患者治疗前、治疗后第5d的凝血及血液流变学指标差异,同时观察两组患者的烧伤愈合情况。结果:治疗前中药组和常规组的全血低切粘度、全血高切黏度、血浆粘度、红细胞聚集指数、红细胞变形指数测定值比较差异均不显著(P>0.05);治疗5d后,两组患者的全血低切粘度、全血高切黏度、血浆粘度、红细胞聚集指数、红细胞变形指数较治疗前均显著缩小(P<0.05),治疗后研究组的上述指标均显著小于常规组(P<0.05)。治疗前两组患者的APTT、AT-Ⅲ:Ag、PC:a测定值比较差异不显著(P>0.05),治疗后两组患者的APTT、AT-Ⅲ:Ag、PC:a测定值较治疗前均显著升高(P<0.05),中药组升高较常规组更加显著(P<0.05)。中药组的水肿消退时间4.4±1.8(d)、创面愈合率77.9±9.4(%)、创面愈合时间7.8±2.1(d)、创面感染率4.88(%)均显著的低于常规组(P<0.05)。中药组的总有效率达到95.12%显著高于常规组的78.05%(P<0.05)。结论:自制黄连膏治疗烧伤血瘀症患者能够显著改善患者的高凝血状态及血液流变学指标,从而提高创面愈合效果。Objective：Discussing on the effect of using the self-made Coptis ointment in the treatment of burned patients who was blood stasis.Methods：Since the department of burn and plastic surgery from January 2013 to December 2014 were treated with early burn in 82 cases,were randomly divided into routine treatment group and Chinese medicine group with 41 cases in each group,the conventional treatment group was treated with conventional therapy of burn,Chinese medicine group with self-made Coptis ointment treatment,compared two groups of patients before treatment,after treatment of coagulation and the 5Dindex of hemorheology differences,at the same time,two groups were observed in patients with burn healing.Results：Before treatment,traditional Chinese medicine group and routine group whole blood low shear viscosity,whole blood high shear viscosity,plasma viscosity,erythrocyte aggregation index,erythrocyte deformation index were compared the difference was not significant（P〉0.05）;after 5Dtreatment,the two groups of patients with whole blood low shear viscosity,whole blood high shear viscosity,plasma viscosity,erythrocyte aggregation index,erythrocyte deformation index were significantly reduced compared with those before treatment（P〈0.05）,the index after the treatment of the study group were significantly lower than that of the conventional group（P〈0.05）In two groups before treatment in patients with APTT,AT-III：Ag,value of PC：was not significant difference（P〉0.05）,the two groups after treatment in patients with APTT,AT-III：Ag,PC：a values were significantly higher than those before treatment（P〈0.05）,the Chinese medicine group increased more significantly than the normal group（P〈0.05）.The traditional Chinese medicine group＇s edema subsiding 4.4±1.8（d）,wound healing rate was 77.9±9.4（%）,the wound healing time was7.8±2.1（d）,wound infection rate was 4.88（%）were significantly lower than that of normal group（P〈0.05）.The efficiency rate was 95.12%higher

关 键 词：黄连膏 烧伤 血瘀证 影响作用 

分 类 号：R644[医药卫生—外科学]