水柏枝化学成分和药理活性的研究进展  

Progress in studies on chemical constituents and pharmacological activities of Myricaria germanica

作　　者：李陆军[1] 张瑛[2] 李帅[2] 

机构地区：[1]黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040 [2]中国医学科学院北京协和医学院药物研究所,北京100050

出　　处：《药物评价研究》2015年第3期331-335,共5页Drug Evaluation Research

基　　金：国家自然科学基金资助项目(21072233)

摘　　要：水柏枝来源于柽柳科水柏枝属植物水柏枝Myricaria germanica及同属多种植物的嫩枝,具有疏风解表、祛风通络、透疹止咳等功效。主要对来源于该属的三春水柏枝M.paniculata、宽苞水柏枝M.bracteata和秀丽水柏枝M.elegans的黄酮类、三萜类、没食子酸类、酚酸类、木脂素类、长链脂肪醇类等6类化学成分以及它们的药理活性研究进展进行综述,包括抗菌、抗炎、细胞免疫、抗疲劳、抗氧化、肝损伤保护,为进一步开发利用该属植物、为新药研发储备先导化合物奠定基础。Myricaria germanica（Tamaricaceae） stems from the twigs in the plants of Myricaria Desv. It has the effects of dispelling wind to resolve exterior syndrome, dispelling pathogenic wind and removing obstruction in the meridians, promoting eruption and relieving a cough. The progress on the research of chemical constituents from M. paniculata, M. bracteata, and M. elegans, which mainly contain flavonoids, triterpenoids, gallic acids, phenolic acids, lignans, and long-chain alkanediols with the pharmacological activities such as antibiosis, anti-imflammation, anti-arthritis, cellular immunity, antifatigue, antioxidant, and hepatoprotective effects, was summarized. It establishs good chemical constituents foundation for development and utilization the resource of Myricaria and new drugs research and development.

关 键 词：水柏枝 三春水柏枝 宽苞水柏枝 秀丽水柏枝 化学成分 药理活性 

分 类 号：R285[医药卫生—中药学]