高强度聚焦超声治疗功能性子宫出血临床初步观察  

Clinical Observation on Treatment of Functional Uterine Bleeding with High Intensity Focused Ultrasound

作　　者：郭艳琴[1] 汪芳[2] 石珍[1] 肖菊花[3] 周金水[2] 张激 黄汉年 

机构地区：[1]南昌大学第一附属医院妇产科,南昌市330006 [2]南昌大学第一附属医院HIFU治疗室,南昌市330006 [3]江西省妇幼保健院超声科 [4]深圳市普罗惠仁医学科技有限公司

出　　处：《中国超声医学杂志》2015年第4期358-360,共3页Chinese Journal of Ultrasound in Medicine

基　　金：卫生部医药卫生科技发展研究中心项目(No.W2013HF09);江西省卫生厅研究项目(No.20155160)

摘　　要：目的 通过随访观察高强度聚焦超声（HIFU）治疗功能性子宫出血（DUB）的临床效果,评估其治疗的安全性及有效性.方法 应用HIFU对子宫内膜的功能层、基底层直至肌层下3 mm进行热辐照,分2～3个治疗层面,1次/d,治疗后随访观察3～12个月.结果 治疗1～3个月后15例闭经,23例月经量明显减少,4例月经量无改变.6～12个月29例闭经,10例月经量减少,3例子宫切除,治疗总有效率达93％ （39/42）.结论 HIFU治疗DUB可能是一种比较安全、有效的新方法.Objective To assess the effectiveness and safety of High intensity focused ultrasound for the treatment of functional uterine bleeding.Methods 42 DUB patients recieved HIFU treatment were selected.Heat radiation wasmade on functional layer,basal layer even to 3 mm under muscle layer of endometry.It is divided by 2～3 layer treatment and one time a day,followed by 3～12 months of observation.Results After treatment for 1～3 months,it resulted in 15 cases of amenorrhoea,23 cases of menstrual quantity obvious reduction and 4 cases of menstrual quantity without changing,after 6～12 months of treatment,it resulted in 29 cases of amenorrhoea,10 cases of menstrual reduction,3 cases of uterine resection treatment,and the total effective rate was 93％ （39/42）.Conclusions HIFU treatment of DUB may be a new methods for relatively safe,effective.

关 键 词：高强度聚焦超声 功能性子宫出血 疗效 热辐照 闭经 

分 类 号：R711.52[医药卫生—妇产科学] R454.3[医药卫生—临床医学]