北京地区儿童肺炎支原体感染的流行病学分析  

Epidemiological Analysis of Pneumonia Mycoplasma Infection of Children in Beijing Region

作　　者：张淑艳[1] 刘杰[1] 赵满仓[1] 

机构地区：[1]北京军区总医院检验科,北京100700

出　　处：《标记免疫分析与临床》2015年第7期620-623,共4页Labeled Immunoassays and Clinical Medicine

摘　　要：目的探讨北京地区儿童肺炎支原体(MP)的病原学流行特点,为临床诊断MP感染提供病原学依据。方法采用间接免疫荧光法检测患儿血清中MP-Ig M抗体,根据性别、年龄和季节的MP阳性率以及合并感染其他病原体的情况进行统计分析。结果 1985例患儿MP-Ig M抗体阳性率为16.52%,男性患儿阳性率(15.55%)与女性患儿阳性率(18.13%)比较差异无统计学意义(P>0.05);各年龄组间MP-Ig M抗体阳性率有显著差异,婴儿组的MP-Ig M抗体阳性率(7.09%)最低,且随着年龄的增长阳性率逐渐上升,学龄期组(51.39%)明显高于其余各年龄组,差异比较有统计学意义(P<0.01);不同季节患儿MP-Ig M抗体检测阳性率有显著差异,秋季和春季的阳性率(27.92%和18.81%)明显高于夏季和冬季的阳性率(10.81%和7.87%),结果比较有统计学意义(P<0.01);328例MP-Ig M抗体阳性患儿中合并感染其他病原体的160例(48.78%),合并感染一种病原体的96例(29.27%),合并感染两种病原体的40例(12.20%),合并感染三种及三种以上病原体的24例(7.32%)。结论本地区儿童MP感染在年龄和季节上存在差异,在性别间无差异,与其他呼吸道病原体混合感染率高。Objective To investigate the prevalent feature of etiology of children with Pneumonia Mycoplasma in Beijing region, and to provide etiology basis for clinical diagnosis of MP. Methods MP- IgM antibody in serum of children patients was detected by indirect immunofluorescence method, and MP positive rate in different gender, age, season and situations of mixed infection with other pathogens infection were then statistical analyzed. Results MP-IgM antibody positive rate in 1985 cases of children patients was 16.52% , and the positive rate between male children（ 15.55% ） and female children（ 18.13% ） had no significant differences （P 〉 0.05 ）. MP- IgM antibody positive rate between different age groups had significant differences, in which infant＇ s group has the lowest（7.09% ） , and with the age growing, the positive rate increased. Compared with the other groups, the positive rate in group of school age was significantly higher（P 〈 0.01 ）. The positive rate of IgM antibody was different in different seasons. The positive rate during autumn （27.92%） and spring （ 18.81% ） was significantly higher than that in summer（ 10.81% ） and winter（7.87% ）. 160 cases out of 328 positively detected cases of MP-IgM were mixed infected with other kind of pathogens（48.78% ）. 96 cases were mixed infected with one kind of pathogens（29.27% ） , while 24 cases were mixed infected with two kinds of pathogens（ 12.20% ）, and mixed infected with three or more pathogens was 40 cases（7.32% ）. Conclusion MP infection rate has differences in age and season, and there＇ s no significant difference between genders of children in this region. The mixed infected rate with other respiratory tract pathogens is high.

关 键 词：肺炎支原体 儿童 间接免疫荧光法 流行病学 

分 类 号：R725.6[医药卫生—儿科]