左室双部位双心室起搏心脏同步化治疗的研究现状  

Current research status of triple-site cardiac resynchronization therapy

作　　者：蒋敏娜 杨达峰[1] 谢启应[1] 杨天伦[1] 

机构地区：[1]中南大学湘雅医院心内科,长沙410008

出　　处：《临床心血管病杂志》2015年第6期586-590,共5页Journal of Clinical Cardiology

摘　　要：心脏再同步化治疗能够有效改善心力衰竭伴心脏收缩不同步患者的心肌重构、提高生活质量,降低再住院率及死亡率,主要得益于心脏收缩同步的恢复。但在接受心脏再同步化治疗的患者中,高达30%~40%的患者未能从中获益,出现无应答,其可能原因大部分应归因于心脏收缩仍然存在不完全同步。左室双部位双心室起搏心脏再同步化治疗理论上能够较常规心脏再同步化治疗进一步提高心脏收缩的再同步性,近年来的临床研究结果也支持这一观点。本文就左室双部位双心室起搏心脏再同步化治疗的研究现状进行综述。Cardiac resynchronization therapy（CRT）can not only effectively improve ventricular remodeling and the quality of life,but also significantly reduce rehospitalization rate and mortality rate in heart failure patients with cardiac desynchronization.This benefit largely due to the recovered desynchronization of ventricular contraction.However,more than 30-40% of the patients experience non-response.They derive no benefit from CRT,which may be explained by incomplete resynchronization.Theoretically,triple-site CRT has advantages in advanced resynchronization compared with conventional CRT;recent clinical studies also support this view.This article will review the current research status of triple-site CRT.

关 键 词：左室双部位双心室起搏心脏同步化治疗 心脏再同步化治疗 无应答 心力衰竭 

分 类 号：R541.7[医药卫生—心血管疾病]