Selective extraction of dimethoate from cucumber samples by use of molecularly imprinted microspheres  

作　　者：Jiao-Jiao Du Rui-Xia Gao Hu Yu Xiao-Jing Li Hui Mu 

机构地区：[1]Department of Chemistry,School of Science,Xi'an Jiaotong University

出　　处：《Journal of Pharmaceutical Analysis》2015年第3期200-206,共7页药物分析学报（英文版）

基　　金：the National Natural Science Foundation of China(No.21305107);the Fundamental Research Funds for the Central Universities(Nos. xjj2013041,08142034)

摘　　要：Molecularly imprinted polymers for dimethoate recognition were synthesized by the precipitation polymerization technique using methyl methacrylate （MMA） as the functional monomer and ethylene glycol dimethacrylate （EGDMA） as the cross-linker. The morphology, adsorption and recognition properties were investigated by scanning electron microscopy （SEM）, static adsorption test, and competitive adsorption test. To obtain the best selectivity and binding performance, the synthesis and adsorption conditions of MIPs were optimized through single factor experiments. Under the optimized conditions, the resultant polymers exhibited uniform size, satisfactory binding capacity and significant selectivity. Furthermore, the imprinted polymers were successfully applied as a specific solid-phase extractants combined with high performance liquid chromatography （HPLC） for determination of dimethoate residues in the cucumber samples. The average recoveries of three spiked samples ranged from 78.5% to 87.9% with the relative standard deviations （RSDs） less than 4.4% and the limit of detection （LOD） obtained for dimethoate as low as 2.3 μg/mL.Molecularly imprinted polymers for dimethoate recognition were synthesized by the precipitation polymerization technique using methyl methacrylate （MMA） as the functional monomer and ethylene glycol dimethacrylate （EGDMA） as the cross-linker. The morphology, adsorption and recognition properties were investigated by scanning electron microscopy （SEM）, static adsorption test, and competitive adsorption test. To obtain the best selectivity and binding performance, the synthesis and adsorption conditions of MIPs were optimized through single factor experiments. Under the optimized conditions, the resultant polymers exhibited uniform size, satisfactory binding capacity and significant selectivity. Furthermore, the imprinted polymers were successfully applied as a specific solid-phase extractants combined with high performance liquid chromatography （HPLC） for determination of dimethoate residues in the cucumber samples. The average recoveries of three spiked samples ranged from 78.5% to 87.9% with the relative standard deviations （RSDs） less than 4.4% and the limit of detection （LOD） obtained for dimethoate as low as 2.3 μg/mL.

关 键 词：Mol^alarly imprintedpolymer  Precipitation polymeriza-tion DIMETHOATE CUCUMBER HPLC 

分 类 号：TQ453[化学工程—农药化工]