湛江市2010～2013年婴儿预防接种后死亡特征分析  

Characteristic of infant death after vaccination in Zhanjiang during 2010-2013

作　　者：戚佩玲[1] 刘宇[2] 马琳[1] 陈剑云[1] 

机构地区：[1]湛江市疾病预防控制中心,广东湛江524037 [2]广东省疾病预防控制中心,广东广州511430

出　　处：《中国热带医学》2015年第6期714-716,共3页China Tropical Medicine

摘　　要：目的分析婴幼儿预防接种后发生死亡的病例,评价预防接种的安全性。方法收集2010~2013年湛江市疑似预防接种异常反应（Adverse Event Following Immunization,AEFI）监测系统报告的监测数据及接种后死亡病例调查资料,采用描述流行病学方法分析病例发生的人群、季节分布和临床诊断,对死亡个案所接种疫苗的安全性数据与死亡发生率进行比较。结果报告的10例婴幼儿预防接种后死亡病例中,4例为偶合症,其死因与预防接种无关;3例为预防接种后＂过敏性休克＂,属于预防接种异常反应;3例死因不明。结论偶合症是婴幼儿预防接种后死亡常见的类型,寒冷季节是预防接种后发生死亡的好发季节,婴儿接种首剂疫苗后应密切观察其身体状况,为便于观察小孩提醒家长不要把小孩背在后背,防止意外发生。Objective To evaluate the safety of vaccine by analyzing the death of infant cases after vaccination . Methods Data from ＂Adverse Events Following Immunization （AEFI） Surveillance System＂ and the information of death cases after immunization in Zhanjiang from 2010 to 2013 were collected.Descriptive epidemiology was used to analyze the characteristics of population distribution,seasonal distribution and clinical diagnosis of the cases. Vaccine safety data and mortality rate of death cases were compared. Results Among the 10 infant death cases reported after vaccination ,4 cases died from coincidental diseases which were not related to vaccination, 3 cases died from anaphylactic shock which was a kind of AEFI ,3 cases were unexplainable. Conclusions Coincidental disease is the main cause of infant death after vaccination and death induced by AEFI mainly occurred in cold weather. Thus infants＇ physical condition after the first dose of the vaccine should be closely observed and parents should not put their children in the back for ease of observation.

关 键 词：婴儿 预防接种 疑似预防接种异常反应 死亡 

分 类 号：R186[医药卫生—流行病学]