针灸疗法对2型糖尿病患者胰岛功能影响的Meta分析  

Meta Analysis of Acupuncture on the Pancreas Islet Function of Patients with Type-2 Diabetes

作　　者：邢春国[1] 孙志[2] 马永春[3] 范群[1] 

机构地区：[1]江苏建康职业学院卫生管理系江苏省医学情报研究所信息中心,江苏南京210029 [2]南京中医药大学针药结合实验室,江苏南京210023 [3]浙江省立同德医院,浙江杭州310012

出　　处：《南京中医药大学学报》2015年第4期397-400,共4页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：江苏省教育厅高校哲学社会科学基金(2013SJB870002);江苏省社会科学基金(14TQD001)

摘　　要：目的系统评价针灸疗法对糖尿病患者胰岛功能的影响。方法检索针灸对糖尿病患者胰岛功能影响的随机对照研究,以胰岛素抵抗指数(HOMA-IR)、胰岛素敏感指数(ISI)等为胰岛功能评价指标,并进行Meta分析。结果 8项研究符合纳入标准,Meta分析结果显示在改善患者空腹血糖[WMD=-0.81,95%CI(-0.98,-0.64),P<0.01]、空腹胰岛素[WMD=-2.67,95%CI=(-3.35,-1.98),P<0.01]、胰岛素抵抗指数[WMD=-1.51,95%CI(-1.96,-1.06),P<0.01],胰岛素敏感指数[WMD=0.80,95%CI(0.36,1.24),P<0.01]等方面,针灸组优于对照组,差异有统计学意义。结论针灸疗法对糖尿病患者胰岛功能有明显的改善作用,适合推广应用。OBJECTIVE To have a systematic evaluation of the influence of acupuncture on patients with type-2 diabetes. METHODS Randomized controlled trials related to this subject were searched. HOMA-IR, ISI were used as the evaluation in- dexes to conduct the Meta analysis. RESULTS Eight researches were selected and the Meta analysis showed that fasting blood --glucose[WMD= --0.81, 95%CI （--0.98, --0.64）, P〈0.01], fasting insulin[WMD = --2.67,95%CI= （--3.35, --1.98）, P〈0.01], insulin resistance index[WMD = -- 1.51,95 % CI （ -- 1.96, -- 1.06）, P 〈0.01], and insulin sensitivity index[WMD = 0.80,95 % CI （0.36,1.24）, P 〈0.01] showed better improvement in the acupuncture groups than the control groups. The difference had statistical significance. CONCLUSION Acupuncture can significantly improve the pancreas islet function of pa- tients with type-2 diabetes and is worthy of widely application.

关 键 词：糖尿病 针灸 胰岛功能 META分析 胰岛素抵抗指数 胰岛素敏感指数 

分 类 号：R246.1[医药卫生—针灸推拿学]