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作 者:肖景华[1] 吴昌银[1] 袁猛[1] 王妮丽[1] 范优荣[1] 杨猛[1] 欧阳亦聃[1] 阮一骏 张启发[1]
机构地区:[1]华中农业大学生命科学技术学院,作物遗传改良国家重点实验室,武汉430070
出 处:《科学通报》2015年第18期1711-1722,共12页Chinese Science Bulletin
基 金:国家高技术研究发展计划(2012AA10A300)资助
摘 要:功能基因组研究是植物生命科学研究的核心领域之一.从少数基因的克隆到重要农艺性状的功能基因组解析,我国水稻功能基因组研究实现了跨越式发展,阐明了水稻育种中的一些重大生物学问题,功能基因组的研究为水稻品种改良和育种技术变革奠定了基础.着眼未来,我国科学家提出了继续推进"水稻2020"研究计划,适时启动水稻4D基因组的发展建议.Functional genomics research is the core field in plant scientific research. As a staple food crop and a reference of monocot plant, tremendous progress has been made in rice functional genomics in China. Various methods and technical platforms have been developed to enable high-throughput analyses and effective determination of gene functions, including: large T-DNA insertion mutant libraries; global gene expression profiles for the entire life cycle of rice growth and development, abiotic and/or biotic conditions; full-length cDNA clones; high-throughput genotyping by whole-genome resequencing; large-scale analyses of metabolome and reliable high- throughput phenotyping platforms, etc. With those enabling tools and genetic resources, large efforts have been focused on identifying genes controlling yield, fertility, superior quality, resistances to biotic and abiotic stresses, and high nutrient-use efficiency. The combination of approaches based on the advances in genomic research has been formulated to develop rice cultivars referred to as Green Super Rice (GSR). We briefly summarize these advances and call for the prospects in future proposed by Chinese scientists: the RICE2020 Project and the RICE 4D Genome Program.
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